Daily Papers

Creating content for a specific identity (ID) has shown significant interest in the field of generative models. In the field of text-to-image generation (T2I), subject-driven content generation has achieved great progress with the ID in the images controllable. However, extending it to video generation is not well explored. In this work, we propose a simple yet effective subject identity controllable video generation framework, termed Video Custom Diffusion (VCD). With a specified subject ID defined by a few images, VCD reinforces the identity information extraction and injects frame-wise correlation at the initialization stage for stable video outputs with identity preserved to a large extent. To achieve this, we propose three novel components that are essential for high-quality ID preservation: 1) an ID module trained with the cropped identity by prompt-to-segmentation to disentangle the ID information and the background noise for more accurate ID token learning; 2) a text-to-video (T2V) VCD module with 3D Gaussian Noise Prior for better inter-frame consistency and 3) video-to-video (V2V) Face VCD and Tiled VCD modules to deblur the face and upscale the video for higher resolution. Despite its simplicity, we conducted extensive experiments to verify that VCD is able to generate stable and high-quality videos with better ID over the selected strong baselines. Besides, due to the transferability of the ID module, VCD is also working well with finetuned text-to-image models available publically, further improving its usability. The codes are available at https://github.com/Zhen-Dong/Magic-Me.

Implicit neural fields have made remarkable progress in reconstructing 3D surfaces from multiple images; however, they encounter challenges when it comes to separating individual objects within a scene. Previous work has attempted to tackle this problem by introducing a framework to train separate signed distance fields (SDFs) simultaneously for each of N objects and using a regularization term to prevent objects from overlapping. However, all of these methods require segmentation masks to be provided, which are not always readily available. We introduce our method, ObjectCarver, to tackle the problem of object separation from just click input in a single view. Given posed multi-view images and a set of user-input clicks to prompt segmentation of the individual objects, our method decomposes the scene into separate objects and reconstructs a high-quality 3D surface for each one. We introduce a loss function that prevents floaters and avoids inappropriate carving-out due to occlusion. In addition, we introduce a novel scene initialization method that significantly speeds up the process while preserving geometric details compared to previous approaches. Despite requiring neither ground truth masks nor monocular cues, our method outperforms baselines both qualitatively and quantitatively. In addition, we introduce a new benchmark dataset for evaluation.

Promptable segmentation typically requires instance-specific manual prompts to guide the segmentation of each desired object. To minimize such a need, task-generic promptable segmentation has been introduced, which employs a single task-generic prompt to segment various images of different objects in the same task. Current methods use Multimodal Large Language Models (MLLMs) to reason detailed instance-specific prompts from a task-generic prompt for improving segmentation accuracy. The effectiveness of this segmentation heavily depends on the precision of these derived prompts. However, MLLMs often suffer hallucinations during reasoning, resulting in inaccurate prompting. While existing methods focus on eliminating hallucinations to improve a model, we argue that MLLM hallucinations can reveal valuable contextual insights when leveraged correctly, as they represent pre-trained large-scale knowledge beyond individual images. In this paper, we utilize hallucinations to mine task-related information from images and verify its accuracy for enhancing precision of the generated prompts. Specifically, we introduce an iterative Prompt-Mask Cycle generation framework (ProMaC) with a prompt generator and a mask generator.The prompt generator uses a multi-scale chain of thought prompting, initially exploring hallucinations for extracting extended contextual knowledge on a test image.These hallucinations are then reduced to formulate precise instance-specific prompts, directing the mask generator to produce masks that are consistent with task semantics by mask semantic alignment. The generated masks iteratively induce the prompt generator to focus more on task-relevant image areas and reduce irrelevant hallucinations, resulting jointly in better prompts and masks. Experiments on 5 benchmarks demonstrate the effectiveness of ProMaC. Code given in https://lwpyh.github.io/ProMaC/.

The primary challenge of cross-domain few-shot segmentation (CD-FSS) is the domain disparity between the training and inference phases, which can exist in either the input data or the target classes. Previous models struggle to learn feature representations that generalize to various unknown domains from limited training domain samples. In contrast, the large-scale visual model SAM, pre-trained on tens of millions of images from various domains and classes, possesses excellent generalizability. In this work, we propose a SAM-aware graph prompt reasoning network (GPRN) that fully leverages SAM to guide CD-FSS feature representation learning and improve prediction accuracy. Specifically, we propose a SAM-aware prompt initialization module (SPI) to transform the masks generated by SAM into visual prompts enriched with high-level semantic information. Since SAM tends to divide an object into many sub-regions, this may lead to visual prompts representing the same semantic object having inconsistent or fragmented features. We further propose a graph prompt reasoning (GPR) module that constructs a graph among visual prompts to reason about their interrelationships and enable each visual prompt to aggregate information from similar prompts, thus achieving global semantic consistency. Subsequently, each visual prompt embeds its semantic information into the corresponding mask region to assist in feature representation learning. To refine the segmentation mask during testing, we also design a non-parameter adaptive point selection module (APS) to select representative point prompts from query predictions and feed them back to SAM to refine inaccurate segmentation results. Experiments on four standard CD-FSS datasets demonstrate that our method establishes new state-of-the-art results. Code: https://github.com/CVL-hub/GPRN.

The realm of computer vision has witnessed a paradigm shift with the advent of foundational models, mirroring the transformative influence of large language models in the domain of natural language processing. This paper delves into the exploration of open-world segmentation, presenting a novel approach called Image Prompt Segmentation (IPSeg) that harnesses the power of vision foundational models. IPSeg lies the principle of a training-free paradigm, which capitalizes on image prompt techniques. Specifically, IPSeg utilizes a single image containing a subjective visual concept as a flexible prompt to query vision foundation models like DINOv2 and Stable Diffusion. Our approach extracts robust features for the prompt image and input image, then matches the input representations to the prompt representations via a novel feature interaction module to generate point prompts highlighting target objects in the input image. The generated point prompts are further utilized to guide the Segment Anything Model to segment the target object in the input image. The proposed method stands out by eliminating the need for exhaustive training sessions, thereby offering a more efficient and scalable solution. Experiments on COCO, PASCAL VOC, and other datasets demonstrate IPSeg's efficacy for flexible open-world segmentation using intuitive image prompts. This work pioneers tapping foundation models for open-world understanding through visual concepts conveyed in images.

Customized image generation, which seeks to synthesize images with consistent characters, holds significant relevance for applications such as storytelling, portrait generation, and character design. However, previous approaches have encountered challenges in preserving characters with high-fidelity consistency due to inadequate feature extraction and concept confusion of reference characters. Therefore, we propose Character-Adapter, a plug-and-play framework designed to generate images that preserve the details of reference characters, ensuring high-fidelity consistency. Character-Adapter employs prompt-guided segmentation to ensure fine-grained regional features of reference characters and dynamic region-level adapters to mitigate concept confusion. Extensive experiments are conducted to validate the effectiveness of Character-Adapter. Both quantitative and qualitative results demonstrate that Character-Adapter achieves the state-of-the-art performance of consistent character generation, with an improvement of 24.8% compared with other methods. Our code will be released at https://github.com/Character-Adapter/Character-Adapte

Multi-task approaches to joint depth and segmentation prediction are well-studied for monocular images. Yet, predictions from a single-view are inherently limited, while multiple views are available in many robotics applications. On the other end of the spectrum, video-based and full 3D methods require numerous frames to perform reconstruction and segmentation. With this work we propose a Multi-View Stereo (MVS) technique for depth prediction that benefits from rich semantic features of the Segment Anything Model (SAM). This enhanced depth prediction, in turn, serves as a prompt to our Transformer-based semantic segmentation decoder. We report the mutual benefit that both tasks enjoy in our quantitative and qualitative studies on the ScanNet dataset. Our approach consistently outperforms single-task MVS and segmentation models, along with multi-task monocular methods.

Leveraging vast training data (SA-1B), the foundation Segment Anything Model (SAM) proposed by Meta AI Research exhibits remarkable generalization and zero-shot capabilities. Nonetheless, as a category-agnostic instance segmentation method, SAM heavily depends on prior manual guidance involving points, boxes, and coarse-grained masks. Additionally, its performance on remote sensing image segmentation tasks has yet to be fully explored and demonstrated. In this paper, we consider designing an automated instance segmentation approach for remote sensing images based on the SAM foundation model, incorporating semantic category information. Inspired by prompt learning, we propose a method to learn the generation of appropriate prompts for SAM input. This enables SAM to produce semantically discernible segmentation results for remote sensing images, which we refer to as RSPrompter. We also suggest several ongoing derivatives for instance segmentation tasks, based on recent developments in the SAM community, and compare their performance with RSPrompter. Extensive experimental results on the WHU building, NWPU VHR-10, and SSDD datasets validate the efficacy of our proposed method. Our code is accessible at https://kyanchen.github.io/RSPrompter.

Weakly-Supervised Semantic Segmentation (WSSS) aims to train segmentation models using image data with only image-level supervision. Since precise pixel-level annotations are not accessible, existing methods typically focus on producing pseudo masks for training segmentation models by refining CAM-like heatmaps. However, the produced heatmaps may capture only the discriminative image regions of object categories or the associated co-occurring backgrounds. To address the issues, we propose a Semantic Prompt Learning for WSSS (SemPLeS) framework, which learns to effectively prompt the CLIP latent space to enhance the semantic alignment between the segmented regions and the target object categories. More specifically, we propose Contrastive Prompt Learning and Prompt-guided Semantic Refinement to learn the prompts that adequately describe and suppress the co-occurring backgrounds associated with each target object category. In this way, SemPLeS can perform better semantic alignment between object regions and the associated class labels, resulting in desired pseudo masks for training the segmentation model. The proposed SemPLeS framework achieves SOTA performance on the standard WSSS benchmarks, PASCAL VOC and MS COCO, and shows compatibility with other WSSS methods. The source codes are provided in the supplementary.

Large Language Models (LLMs) demonstrate strong capabilities in broad knowledge representation, yet they are inherently deficient in pixel-level perceptual understanding. Although the Segment Anything Model (SAM) represents a significant advancement in visual-prompt-driven image segmentation, it exhibits notable limitations in multi-mask prediction and category-specific segmentation tasks, and it cannot integrate all segmentation tasks within a unified model architecture. To address these limitations, we present X-SAM, a streamlined Multimodal Large Language Model (MLLM) framework that extends the segmentation paradigm from segment anything to any segmentation. Specifically, we introduce a novel unified framework that enables more advanced pixel-level perceptual comprehension for MLLMs. Furthermore, we propose a new segmentation task, termed Visual GrounDed (VGD) segmentation, which segments all instance objects with interactive visual prompts and empowers MLLMs with visual grounded, pixel-wise interpretative capabilities. To enable effective training on diverse data sources, we present a unified training strategy that supports co-training across multiple datasets. Experimental results demonstrate that X-SAM achieves state-of-the-art performance on a wide range of image segmentation benchmarks, highlighting its efficiency for multimodal, pixel-level visual understanding. Code is available at https://github.com/wanghao9610/X-SAM.

Medical image analysis is critical yet challenged by the need of jointly segmenting organs or tissues, and numerous instances for anatomical structures and tumor microenvironment analysis. Existing studies typically formulated different segmentation tasks in isolation, which overlooks the fundamental interdependencies between these tasks, leading to suboptimal segmentation performance and insufficient medical image understanding. To address this issue, we propose a Co-Seg++ framework for versatile medical segmentation. Specifically, we introduce a novel co-segmentation paradigm, allowing semantic and instance segmentation tasks to mutually enhance each other. We first devise a spatio-temporal prompt encoder (STP-Encoder) to capture long-range spatial and temporal relationships between segmentation regions and image embeddings as prior spatial constraints. Moreover, we devise a multi-task collaborative decoder (MTC-Decoder) that leverages cross-guidance to strengthen the contextual consistency of both tasks, jointly computing semantic and instance segmentation masks. Extensive experiments on diverse CT and histopathology datasets demonstrate that the proposed Co-Seg++ outperforms state-of-the-arts in the semantic, instance, and panoptic segmentation of dental anatomical structures, histopathology tissues, and nuclei instances. The source code is available at https://github.com/xq141839/Co-Seg-Plus.

Open-set image segmentation poses a significant challenge because existing methods often demand extensive training or fine-tuning and generally struggle to segment unified objects consistently across diverse text reference expressions. Motivated by this, we propose Segment Anyword, a novel training-free visual concept prompt learning approach for open-set language grounded segmentation that relies on token-level cross-attention maps from a frozen diffusion model to produce segmentation surrogates or mask prompts, which are then refined into targeted object masks. Initial prompts typically lack coherence and consistency as the complexity of the image-text increases, resulting in suboptimal mask fragments. To tackle this issue, we further introduce a novel linguistic-guided visual prompt regularization that binds and clusters visual prompts based on sentence dependency and syntactic structural information, enabling the extraction of robust, noise-tolerant mask prompts, and significant improvements in segmentation accuracy. The proposed approach is effective, generalizes across different open-set segmentation tasks, and achieves state-of-the-art results of 52.5 (+6.8 relative) mIoU on Pascal Context 59, 67.73 (+25.73 relative) cIoU on gRefCOCO, and 67.4 (+1.1 relative to fine-tuned methods) mIoU on GranDf, which is the most complex open-set grounded segmentation task in the field.

Web platforms, mobile applications, and connected sensing systems generate multivariate time series with states at multiple levels of granularity, from coarse regimes to fine-grained events. Effective segmentation in these settings requires integrating across granularities while supporting iterative refinement through sparse prompt signals, which provide a compact mechanism for injecting domain knowledge. Yet existing prompting approaches for time series segmentation operate only within local contexts, so the effect of a prompt quickly fades and cannot guide predictions across the entire sequence. To overcome this limitation, we propose MemPromptTSS, a framework for iterative multi-granularity segmentation that introduces persistent prompt memory. A memory encoder transforms prompts and their surrounding subsequences into memory tokens stored in a bank. This persistent memory enables each new prediction to condition not only on local cues but also on all prompts accumulated across iterations, ensuring their influence persists across the entire sequence. Experiments on six datasets covering wearable sensing and industrial monitoring show that MemPromptTSS achieves 23% and 85% accuracy improvements over the best baseline in single- and multi-granularity segmentation under single iteration inference, and provides stronger refinement in iterative inference with average per-iteration gains of 2.66 percentage points compared to 1.19 for PromptTSS. These results highlight the importance of persistent memory for prompt-guided segmentation, establishing MemPromptTSS as a practical and effective framework for real-world applications.

Precision medicine, such as patient-adaptive treatments assisted by medical image analysis, poses new challenges for segmentation algorithms in adapting to new patients, due to the large variability across different patients and the limited availability of annotated data for each patient. In this work, we propose a data-efficient segmentation algorithm, namely Part-aware Prompted Segment Anything Model (P^2SAM). Without any model fine-tuning, P^2SAM enables seamless adaptation to any new patients relying only on one-shot patient-specific data. We introduce a novel part-aware prompt mechanism to select multiple-point prompts based on the part-level features of the one-shot data, which can be extensively integrated into different promptable segmentation models, such as SAM and SAM 2. Moreover, to determine the optimal number of parts for each specific case, we propose a distribution-guided retrieval approach that further enhances the robustness of the part-aware prompt mechanism. P^2SAM improves the performance by +8.0% and +2.0% mean Dice score for two different patient-adaptive segmentation applications, respectively. In addition, P^2SAM also exhibits impressive generalizability in other adaptive segmentation tasks in the natural image domain, e.g., +6.4% mIoU within personalized object segmentation task. The code is available at: https://github.com/Zch0414/p2sam

We present a novel framework, i.e., Segment Any Anomaly + (SAA+), for zero-shot anomaly segmentation with hybrid prompt regularization to improve the adaptability of modern foundation models. Existing anomaly segmentation models typically rely on domain-specific fine-tuning, limiting their generalization across countless anomaly patterns. In this work, inspired by the great zero-shot generalization ability of foundation models like Segment Anything, we first explore their assembly to leverage diverse multi-modal prior knowledge for anomaly localization. For non-parameter foundation model adaptation to anomaly segmentation, we further introduce hybrid prompts derived from domain expert knowledge and target image context as regularization. Our proposed SAA+ model achieves state-of-the-art performance on several anomaly segmentation benchmarks, including VisA, MVTec-AD, MTD, and KSDD2, in the zero-shot setting. We will release the code at https://github.com/caoyunkang/Segment-Any-Anomaly{https://github.com/caoyunkang/Segment-Any-Anomaly}.

Existing Referring Image Segmentation (RIS) methods typically require expensive pixel-level or box-level annotations for supervision. In this paper, we observe that the referring texts used in RIS already provide sufficient information to localize the target object. Hence, we propose a novel weakly-supervised RIS framework to formulate the target localization problem as a classification process to differentiate between positive and negative text expressions. While the referring text expressions for an image are used as positive expressions, the referring text expressions from other images can be used as negative expressions for this image. Our framework has three main novelties. First, we propose a bilateral prompt method to facilitate the classification process, by harmonizing the domain discrepancy between visual and linguistic features. Second, we propose a calibration method to reduce noisy background information and improve the correctness of the response maps for target object localization. Third, we propose a positive response map selection strategy to generate high-quality pseudo-labels from the enhanced response maps, for training a segmentation network for RIS inference. For evaluation, we propose a new metric to measure localization accuracy. Experiments on four benchmarks show that our framework achieves promising performances to existing fully-supervised RIS methods while outperforming state-of-the-art weakly-supervised methods adapted from related areas. Code is available at https://github.com/fawnliu/TRIS.

Referring Video Object Segmentation (RVOS) aims to segment the object referred to by the query sentence throughout the entire video. Most existing methods require end-to-end training with dense mask annotations, which could be computation-consuming and less scalable. In this work, we aim to efficiently adapt foundation segmentation models for addressing RVOS from weak supervision with the proposed Grounded Prompting (GroPrompt) framework. More specifically, we propose Text-Aware Prompt Contrastive Learning (TAP-CL) to enhance the association between the position prompts and the referring sentences with only box supervisions, including Text-Contrastive Prompt Learning (TextCon) and Modality-Contrastive Prompt Learning (ModalCon) at frame level and video level, respectively. With the proposed TAP-CL, our GroPrompt framework can generate temporal-consistent yet text-aware position prompts describing locations and movements for the referred object from the video. The experimental results in the standard RVOS benchmarks (Ref-YouTube-VOS, Ref-DAVIS17, A2D-Sentences, and JHMDB-Sentences) demonstrate the competitive performance of our proposed GroPrompt framework given only bounding box weak supervisions.

Recently, a few open-vocabulary methods have been proposed by employing a unified architecture to tackle generic segmentation and detection tasks. However, their performance still lags behind the task-specific models due to the conflict between different tasks, and their open-vocabulary capability is limited due to the inadequate use of CLIP. To address these challenges, we present a universal transformer-based framework, abbreviated as OpenSD, which utilizes the same architecture and network parameters to handle open-vocabulary segmentation and detection tasks. First, we introduce a decoder decoupled learning strategy to alleviate the semantic conflict between thing and staff categories so that each individual task can be learned more effectively under the same framework. Second, to better leverage CLIP for end-to-end segmentation and detection, we propose dual classifiers to handle the in-vocabulary domain and out-of-vocabulary domain, respectively. The text encoder is further trained to be region-aware for both thing and stuff categories through decoupled prompt learning, enabling them to filter out duplicated and low-quality predictions, which is important to end-to-end segmentation and detection. Extensive experiments are conducted on multiple datasets under various circumstances. The results demonstrate that OpenSD outperforms state-of-the-art open-vocabulary segmentation and detection methods in both closed- and open-vocabulary settings. Code is available at https://github.com/strongwolf/OpenSD

Multi-organ medical segmentation is a crucial component of medical image processing, essential for doctors to make accurate diagnoses and develop effective treatment plans. Despite significant progress in this field, current multi-organ segmentation models often suffer from inaccurate details, dependence on geometric prompts and loss of spatial information. Addressing these challenges, we introduce a novel model named CRISP-SAM2 with CRoss-modal Interaction and Semantic Prompting based on SAM2. This model represents a promising approach to multi-organ medical segmentation guided by textual descriptions of organs. Our method begins by converting visual and textual inputs into cross-modal contextualized semantics using a progressive cross-attention interaction mechanism. These semantics are then injected into the image encoder to enhance the detailed understanding of visual information. To eliminate reliance on geometric prompts, we use a semantic prompting strategy, replacing the original prompt encoder to sharpen the perception of challenging targets. In addition, a similarity-sorting self-updating strategy for memory and a mask-refining process is applied to further adapt to medical imaging and enhance localized details. Comparative experiments conducted on seven public datasets indicate that CRISP-SAM2 outperforms existing models. Extensive analysis also demonstrates the effectiveness of our method, thereby confirming its superior performance, especially in addressing the limitations mentioned earlier. Our code is available at: https://github.com/YU-deep/CRISP\_SAM2.git.

Cross-view object correspondence, exemplified by the representative task of ego-exo object correspondence, aims to establish consistent associations of the same object across different viewpoints (e.g., ego-centric and exo-centric). This task poses significant challenges due to drastic viewpoint and appearance variations, making existing segmentation models, such as SAM2, non-trivial to apply directly. To address this, we present V^2-SAM, a unified cross-view object correspondence framework that adapts SAM2 from single-view segmentation to cross-view correspondence through two complementary prompt generators. Specifically, the Cross-View Anchor Prompt Generator (V^2-Anchor), built upon DINOv3 features, establishes geometry-aware correspondences and, for the first time, unlocks coordinate-based prompting for SAM2 in cross-view scenarios, while the Cross-View Visual Prompt Generator (V^2-Visual) enhances appearance-guided cues via a novel visual prompt matcher that aligns ego-exo representations from both feature and structural perspectives. To effectively exploit the strengths of both prompts, we further adopt a multi-expert design and introduce a Post-hoc Cyclic Consistency Selector (PCCS) that adaptively selects the most reliable expert based on cyclic consistency. Extensive experiments validate the effectiveness of V^2-SAM, achieving new state-of-the-art performance on Ego-Exo4D (ego-exo object correspondence), DAVIS-2017 (video object tracking), and HANDAL-X (robotic-ready cross-view correspondence).

Real-time, on-device segmentation is critical for latency-sensitive and privacy-aware applications like smart glasses and IoT devices. We introduce PicoSAM2, a lightweight (1.3M parameters, 336M MACs) promptable segmentation model optimized for edge and in-sensor execution, including the Sony IMX500. It builds on a depthwise separable U-Net, with knowledge distillation and fixed-point prompt encoding to learn from the Segment Anything Model 2 (SAM2). On COCO and LVIS, it achieves 51.9% and 44.9% mIoU, respectively. The quantized model (1.22MB) runs at 14.3 ms on the IMX500-achieving 86 MACs/cycle, making it the only model meeting both memory and compute constraints for in-sensor deployment. Distillation boosts LVIS performance by +3.5% mIoU and +5.1% mAP. These results demonstrate that efficient, promptable segmentation is feasible directly on-camera, enabling privacy-preserving vision without cloud or host processing.

Exploring open-world situations in an end-to-end manner is a promising yet challenging task due to the need for strong generalization capabilities. In particular, end-to-end autonomous driving in unstructured outdoor environments often encounters conditions that were unfamiliar during training. In this work, we present Vision-Language Action Retrieval (VLA-R), an open-world end-to-end autonomous driving (OW-E2EAD) framework that integrates open-world perception with a novel vision-action retrieval paradigm. We leverage a frozen vision-language model for open-world detection and segmentation to obtain multi-scale, prompt-guided, and interpretable perception features without domain-specific tuning. A Q-Former bottleneck aggregates fine-grained visual representations with language-aligned visual features, bridging perception and action domains. To learn transferable driving behaviors, we introduce a vision-action contrastive learning scheme that aligns vision-language and action embeddings for effective open-world reasoning and action retrieval. Our experiments on a real-world robotic platform demonstrate strong generalization and exploratory performance in unstructured, unseen environments, even with limited data. Demo videos are provided in the supplementary material.

In the era of information explosion, efficiently leveraging large-scale unlabeled data while minimizing the reliance on high-quality pixel-level annotations remains a critical challenge in the field of medical imaging. Semi-supervised learning (SSL) enhances the utilization of unlabeled data by facilitating knowledge transfer, significantly improving the performance of fully supervised models and emerging as a highly promising research direction in medical image analysis. Inspired by the ability of Vision Foundation Models (e.g., SAM-2) to provide rich prior knowledge, we propose SSS (Semi-Supervised SAM-2), a novel approach that leverages SAM-2's robust feature extraction capabilities to uncover latent knowledge in unlabeled medical images, thus effectively enhancing feature support for fully supervised medical image segmentation. Specifically, building upon the single-stream "weak-to-strong" consistency regularization framework, this paper introduces a Discriminative Feature Enhancement (DFE) mechanism to further explore the feature discrepancies introduced by various data augmentation strategies across multiple views. By leveraging feature similarity and dissimilarity across multi-scale augmentation techniques, the method reconstructs and models the features, thereby effectively optimizing the salient regions. Furthermore, a prompt generator is developed that integrates Physical Constraints with a Sliding Window (PCSW) mechanism to generate input prompts for unlabeled data, fulfilling SAM-2's requirement for additional prompts. Extensive experiments demonstrate the superiority of the proposed method for semi-supervised medical image segmentation on two multi-label datasets, i.e., ACDC and BHSD. Notably, SSS achieves an average Dice score of 53.15 on BHSD, surpassing the previous state-of-the-art method by +3.65 Dice. Code will be available at https://github.com/AIGeeksGroup/SSS.

Diffusion models represent a new paradigm in text-to-image generation. Beyond generating high-quality images from text prompts, models such as Stable Diffusion have been successfully extended to the joint generation of semantic segmentation pseudo-masks. However, current extensions primarily rely on extracting attentions linked to prompt words used for image synthesis. This approach limits the generation of segmentation masks derived from word tokens not contained in the text prompt. In this work, we introduce Open-Vocabulary Attention Maps (OVAM)-a training-free method for text-to-image diffusion models that enables the generation of attention maps for any word. In addition, we propose a lightweight optimization process based on OVAM for finding tokens that generate accurate attention maps for an object class with a single annotation. We evaluate these tokens within existing state-of-the-art Stable Diffusion extensions. The best-performing model improves its mIoU from 52.1 to 86.6 for the synthetic images' pseudo-masks, demonstrating that our optimized tokens are an efficient way to improve the performance of existing methods without architectural changes or retraining.

We present SAM4EM, a novel approach for 3D segmentation of complex neural structures in electron microscopy (EM) data by leveraging the Segment Anything Model (SAM) alongside advanced fine-tuning strategies. Our contributions include the development of a prompt-free adapter for SAM using two stage mask decoding to automatically generate prompt embeddings, a dual-stage fine-tuning method based on Low-Rank Adaptation (LoRA) for enhancing segmentation with limited annotated data, and a 3D memory attention mechanism to ensure segmentation consistency across 3D stacks. We further release a unique benchmark dataset for the segmentation of astrocytic processes and synapses. We evaluated our method on challenging neuroscience segmentation benchmarks, specifically targeting mitochondria, glia, and synapses, with significant accuracy improvements over state-of-the-art (SOTA) methods, including recent SAM-based adapters developed for the medical domain and other vision transformer-based approaches. Experimental results indicate that our approach outperforms existing solutions in the segmentation of complex processes like glia and post-synaptic densities. Our code and models are available at https://github.com/Uzshah/SAM4EM.

We propose Point'n Move, a method that achieves interactive scene object manipulation with exposed region inpainting. Interactivity here further comes from intuitive object selection and real-time editing. To achieve this, we adopt Gaussian Splatting Radiance Field as the scene representation and fully leverage its explicit nature and speed advantage. Its explicit representation formulation allows us to devise a 2D prompt points to 3D mask dual-stage self-prompting segmentation algorithm, perform mask refinement and merging, minimize change as well as provide good initialization for scene inpainting and perform editing in real-time without per-editing training, all leads to superior quality and performance. We test our method by performing editing on both forward-facing and 360 scenes. We also compare our method against existing scene object removal methods, showing superior quality despite being more capable and having a speed advantage.

Given a single labeled example, in-context segmentation aims to segment corresponding objects. This setting, known as one-shot segmentation in few-shot learning, explores the segmentation model's generalization ability and has been applied to various vision tasks, including scene understanding and image/video editing. While recent Segment Anything Models have achieved state-of-the-art results in interactive segmentation, these approaches are not directly applicable to in-context segmentation. In this work, we propose the Dual Consistency SAM (DC-SAM) method based on prompt-tuning to adapt SAM and SAM2 for in-context segmentation of both images and videos. Our key insights are to enhance the features of the SAM's prompt encoder in segmentation by providing high-quality visual prompts. When generating a mask prior, we fuse the SAM features to better align the prompt encoder. Then, we design a cycle-consistent cross-attention on fused features and initial visual prompts. Next, a dual-branch design is provided by using the discriminative positive and negative prompts in the prompt encoder. Furthermore, we design a simple mask-tube training strategy to adopt our proposed dual consistency method into the mask tube. Although the proposed DC-SAM is primarily designed for images, it can be seamlessly extended to the video domain with the support of SAM2. Given the absence of in-context segmentation in the video domain, we manually curate and construct the first benchmark from existing video segmentation datasets, named In-Context Video Object Segmentation (IC-VOS), to better assess the in-context capability of the model. Extensive experiments demonstrate that our method achieves 55.5 (+1.4) mIoU on COCO-20i, 73.0 (+1.1) mIoU on PASCAL-5i, and a J&F score of 71.52 on the proposed IC-VOS benchmark. Our source code and benchmark are available at https://github.com/zaplm/DC-SAM.

Open-vocabulary semantic segmentation aims to segment images into distinct semantic regions for both seen and unseen categories at the pixel level. Current methods utilize text embeddings from pre-trained vision-language models like CLIP but struggle with the inherent domain gap between image and text embeddings, even after extensive alignment during training. Additionally, relying solely on deep text-aligned features limits shallow-level feature guidance, which is crucial for detecting small objects and fine details, ultimately reducing segmentation accuracy. To address these limitations, we propose a dual prompting framework, DPSeg, for this task. Our approach combines dual-prompt cost volume generation, a cost volume-guided decoder, and a semantic-guided prompt refinement strategy that leverages our dual prompting scheme to mitigate alignment issues in visual prompt generation. By incorporating visual embeddings from a visual prompt encoder, our approach reduces the domain gap between text and image embeddings while providing multi-level guidance through shallow features. Extensive experiments demonstrate that our method significantly outperforms existing state-of-the-art approaches on multiple public datasets.

The Segment Anything Model (SAM) has exhibited outstanding performance in various image segmentation tasks. Despite being trained with over a billion masks, SAM faces challenges in mask prediction quality in numerous scenarios, especially in real-world contexts. In this paper, we introduce a novel prompt-driven adapter into SAM, namely Prompt Adapter Segment Anything Model (PA-SAM), aiming to enhance the segmentation mask quality of the original SAM. By exclusively training the prompt adapter, PA-SAM extracts detailed information from images and optimizes the mask decoder feature at both sparse and dense prompt levels, improving the segmentation performance of SAM to produce high-quality masks. Experimental results demonstrate that our PA-SAM outperforms other SAM-based methods in high-quality, zero-shot, and open-set segmentation. We're making the source code and models available at https://github.com/xzz2/pa-sam.

Pancreatic cancer carries a poor prognosis and relies on endoscopic ultrasound (EUS) for targeted biopsy and radiotherapy. However, the speckle noise, low contrast, and unintuitive appearance of EUS make segmentation of pancreatic tumors with fully supervised deep learning (DL) models both error-prone and dependent on large, expert-curated annotation datasets. To address these challenges, we present TextSAM-EUS, a novel, lightweight, text-driven adaptation of the Segment Anything Model (SAM) that requires no manual geometric prompts at inference. Our approach leverages text prompt learning (context optimization) through the BiomedCLIP text encoder in conjunction with a LoRA-based adaptation of SAM's architecture to enable automatic pancreatic tumor segmentation in EUS, tuning only 0.86% of the total parameters. On the public Endoscopic Ultrasound Database of the Pancreas, TextSAM-EUS with automatic prompts attains 82.69% Dice and 85.28% normalized surface distance (NSD), and with manual geometric prompts reaches 83.10% Dice and 85.70% NSD, outperforming both existing state-of-the-art (SOTA) supervised DL models and foundation models (e.g., SAM and its variants). As the first attempt to incorporate prompt learning in SAM-based medical image segmentation, TextSAM-EUS offers a practical option for efficient and robust automatic EUS segmentation. Code is available at https://github.com/HealthX-Lab/TextSAM-EUS .

Vision-Language Models (VLMs) have shown impressive performance in vision tasks, but adapting them to new domains often requires expensive fine-tuning. Prompt tuning techniques, including textual, visual, and multimodal prompting, offer efficient alternatives by leveraging learnable prompts. However, their application to Vision-Language Segmentation Models (VLSMs) and evaluation under significant domain shifts remain unexplored. This work presents an open-source benchmarking framework, TuneVLSeg, to integrate various unimodal and multimodal prompt tuning techniques into VLSMs, making prompt tuning usable for downstream segmentation datasets with any number of classes. TuneVLSeg includes 6 prompt tuning strategies on various prompt depths used in 2 VLSMs totaling of 8 different combinations. We test various prompt tuning on 8 diverse medical datasets, including 3 radiology datasets (breast tumor, echocardiograph, chest X-ray pathologies) and 5 non-radiology datasets (polyp, ulcer, skin cancer), and two natural domain segmentation datasets. Our study found that textual prompt tuning struggles under significant domain shifts, from natural-domain images to medical data. Furthermore, visual prompt tuning, with fewer hyperparameters than multimodal prompt tuning, often achieves performance competitive to multimodal approaches, making it a valuable first attempt. Our work advances the understanding and applicability of different prompt-tuning techniques for robust domain-specific segmentation. The source code is available at https://github.com/naamiinepal/tunevlseg.

Unsupervised reconstruction networks using self-attention transformers have achieved state-of-the-art performance for multi-class (unified) anomaly detection with a single model. However, these self-attention reconstruction models primarily operate on target features, which may result in perfect reconstruction for both normal and anomaly features due to high consistency with context, leading to failure in detecting anomalies. Additionally, these models often produce inaccurate anomaly segmentation due to performing reconstruction in a low spatial resolution latent space. To enable reconstruction models enjoying high efficiency while enhancing their generalization for unified anomaly detection, we propose a simple yet effective method that reconstructs normal features and restores anomaly features with just One Normal Image Prompt (OneNIP). In contrast to previous work, OneNIP allows for the first time to reconstruct or restore anomalies with just one normal image prompt, effectively boosting unified anomaly detection performance. Furthermore, we propose a supervised refiner that regresses reconstruction errors by using both real normal and synthesized anomalous images, which significantly improves pixel-level anomaly segmentation. OneNIP outperforms previous methods on three industry anomaly detection benchmarks: MVTec, BTAD, and VisA. The code and pre-trained models are available at https://github.com/gaobb/OneNIP.

We introduce Medal S, a medical segmentation foundation model that supports native-resolution spatial and textual prompts within an end-to-end trainable framework. Unlike text-only methods lacking spatial awareness, Medal S achieves channel-wise alignment between volumetric prompts and text embeddings, mitigating inaccuracies from resolution mismatches. By preserving full 3D context, it efficiently processes multiple native-resolution masks in parallel, enhancing multi-class segmentation performance. A lightweight 3D convolutional module enables precise voxel-space refinement guided by both prompt types, supporting up to 243 classes across CT, MRI, PET, ultrasound, and microscopy modalities in the BiomedSegFM dataset. Medal S offers two prompting modes: a text-only mode, where model predictions serve as spatial prompts for self-refinement without human input, and a hybrid mode, incorporating manual annotations for enhanced flexibility. For 24-class segmentation, parallel spatial prompting reduces inference time by more than 90% compared to sequential prompting. We propose dynamic resampling to address target-patch ratio imbalance, extending SAT and nnU-Net for data augmentation. Furthermore, we develop optimized text preprocessing, a two-stage inference strategy, and post-processing techniques to improve memory efficiency, precision, and inference speed. On the five-modality average on the validation set, Medal S outperforms SAT with a DSC of 75.44 (vs. 69.83), NSD of 77.34 (vs. 71.06), F1 of 38.24 (vs. 24.88), and DSC TP of 65.46 (vs. 46.97). Medal S achieves excellent performance by harmonizing spatial precision with semantic textual guidance, demonstrating superior efficiency and accuracy in multi-class medical segmentation tasks compared to sequential prompt-based approaches. Medal S will be publicly available at https://github.com/yinghemedical/Medal-S.

The performance of image segmentation models has historically been constrained by the high cost of collecting large-scale annotated data. The Segment Anything Model (SAM) alleviates this original problem through a promptable, semantics-agnostic, segmentation paradigm and yet still requires manual visual-prompts or complex domain-dependent prompt-generation rules to process a new image. Towards reducing this new burden, our work investigates the task of object segmentation when provided with, alternatively, only a small set of reference images. Our key insight is to leverage strong semantic priors, as learned by foundation models, to identify corresponding regions between a reference and a target image. We find that correspondences enable automatic generation of instance-level segmentation masks for downstream tasks and instantiate our ideas via a multi-stage, training-free method incorporating (1) memory bank construction; (2) representation aggregation and (3) semantic-aware feature matching. Our experiments show significant improvements on segmentation metrics, leading to state-of-the-art performance on COCO FSOD (36.8% nAP), PASCAL VOC Few-Shot (71.2% nAP50) and outperforming existing training-free approaches on the Cross-Domain FSOD benchmark (22.4% nAP).

Segmenting and recognizing diverse object parts is crucial in computer vision and robotics. Despite significant progress in object segmentation, part-level segmentation remains underexplored due to complex boundaries and scarce annotated data. To address this, we propose a novel Weakly-supervised Part Segmentation (WPS) setting and an approach called WPS-SAM, built on the large-scale pre-trained vision foundation model, Segment Anything Model (SAM). WPS-SAM is an end-to-end framework designed to extract prompt tokens directly from images and perform pixel-level segmentation of part regions. During its training phase, it only uses weakly supervised labels in the form of bounding boxes or points. Extensive experiments demonstrate that, through exploiting the rich knowledge embedded in pre-trained foundation models, WPS-SAM outperforms other segmentation models trained with pixel-level strong annotations. Specifically, WPS-SAM achieves 68.93% mIOU and 79.53% mACC on the PartImageNet dataset, surpassing state-of-the-art fully supervised methods by approximately 4% in terms of mIOU.

Recently, transformer-based models have demonstrated remarkable performance on audio-visual segmentation (AVS) tasks. However, their expensive computational cost makes real-time inference impractical. By characterizing attention maps of the network, we identify two key obstacles in AVS models: 1) attention dissipation, corresponding to the over-concentrated attention weights by Softmax within restricted frames, and 2) inefficient, burdensome transformer decoder, caused by narrow focus patterns in early stages. In this paper, we introduce AVESFormer, the first real-time Audio-Visual Efficient Segmentation transformer that achieves fast, efficient and light-weight simultaneously. Our model leverages an efficient prompt query generator to correct the behaviour of cross-attention. Additionally, we propose ELF decoder to bring greater efficiency by facilitating convolutions suitable for local features to reduce computational burdens. Extensive experiments demonstrate that our AVESFormer significantly enhances model performance, achieving 79.9% on S4, 57.9% on MS3 and 31.2% on AVSS, outperforming previous state-of-the-art and achieving an excellent trade-off between performance and speed. Code can be found at https://github.com/MarkXCloud/AVESFormer.git.

Referring Video Object Segmentation (RVOS) aims to segment the object referred to by the query sentence in the video. Most existing methods require end-to-end training with dense mask annotations, which could be computation-consuming and less scalable. In this work, we rethink the RVOS problem and aim to investigate the key to this task. Based on existing foundation segmentation models, we decompose the RVOS task into referring, video, and segmentation factors, and propose a Temporal Prompt Generation and Selection (Tenet) framework to address the referring and video factors while leaving the segmentation problem to foundation models. To efficiently adapt image-based foundation segmentation models to referring video object segmentation, we leverage off-the-shelf object detectors and trackers to produce temporal prompts associated with the referring sentence. While high-quality temporal prompts could be produced, they can not be easily identified from confidence scores. To tackle this issue, we propose Prompt Preference Learning to evaluate the quality of the produced temporal prompts. By taking such prompts to instruct image-based foundation segmentation models, we would be able to produce high-quality masks for the referred object, enabling efficient model adaptation to referring video object segmentation. Experiments on RVOS benchmarks demonstrate the effectiveness of the Tenet framework.

Medical image segmentation has immense clinical applicability but remains a challenge despite advancements in deep learning. The Segment Anything Model (SAM) exhibits potential in this field, yet the requirement for expertise intervention and the domain gap between natural and medical images poses significant obstacles. This paper introduces a novel training-free evidential prompt generation method named EviPrompt to overcome these issues. The proposed method, built on the inherent similarities within medical images, requires only a single reference image-annotation pair, making it a training-free solution that significantly reduces the need for extensive labeling and computational resources. First, to automatically generate prompts for SAM in medical images, we introduce an evidential method based on uncertainty estimation without the interaction of clinical experts. Then, we incorporate the human prior into the prompts, which is vital for alleviating the domain gap between natural and medical images and enhancing the applicability and usefulness of SAM in medical scenarios. EviPrompt represents an efficient and robust approach to medical image segmentation, with evaluations across a broad range of tasks and modalities confirming its efficacy.

Unseen Object Instance Segmentation (UOIS) is crucial for autonomous robots operating in unstructured environments. Previous approaches require full supervision on large-scale tabletop datasets for effective pretraining. In this paper, we propose UOIS-SAM, a data-efficient solution for the UOIS task that leverages SAM's high accuracy and strong generalization capabilities. UOIS-SAM integrates two key components: (i) a Heatmap-based Prompt Generator (HPG) to generate class-agnostic point prompts with precise foreground prediction, and (ii) a Hierarchical Discrimination Network (HDNet) that adapts SAM's mask decoder, mitigating issues introduced by the SAM baseline, such as background confusion and over-segmentation, especially in scenarios involving occlusion and texture-rich objects. Extensive experimental results on OCID, OSD, and additional photometrically challenging datasets including PhoCAL and HouseCat6D, demonstrate that, even using only 10% of the training samples compared to previous methods, UOIS-SAM achieves state-of-the-art performance in unseen object segmentation, highlighting its effectiveness and robustness in various tabletop scenes.

With recent breakthroughs in large-scale modeling, the Segment Anything Model (SAM) has demonstrated significant potential in a variety of visual applications. However, due to the lack of underwater domain expertise, SAM and its variants face performance limitations in end-to-end underwater instance segmentation tasks, while their higher computational requirements further hinder their application in underwater scenarios. To address this challenge, we propose a large-scale underwater instance segmentation dataset, UIIS10K, which includes 10,048 images with pixel-level annotations for 10 categories. Then, we introduce UWSAM, an efficient model designed for automatic and accurate segmentation of underwater instances. UWSAM efficiently distills knowledge from the SAM ViT-Huge image encoder into the smaller ViT-Small image encoder via the Mask GAT-based Underwater Knowledge Distillation (MG-UKD) method for effective visual representation learning. Furthermore, we design an End-to-end Underwater Prompt Generator (EUPG) for UWSAM, which automatically generates underwater prompts instead of explicitly providing foreground points or boxes as prompts, thus enabling the network to locate underwater instances accurately for efficient segmentation. Comprehensive experimental results show that our model is effective, achieving significant performance improvements over state-of-the-art methods on multiple underwater instance datasets. Datasets and codes are available at https://github.com/LiamLian0727/UIIS10K.

LLaVA-Interactive is a research prototype for multimodal human-AI interaction. The system can have multi-turn dialogues with human users by taking multimodal user inputs and generating multimodal responses. Importantly, LLaVA-Interactive goes beyond language prompt, where visual prompt is enabled to align human intents in the interaction. The development of LLaVA-Interactive is extremely cost-efficient as the system combines three multimodal skills of pre-built AI models without additional model training: visual chat of LLaVA, image segmentation from SEEM, as well as image generation and editing from GLIGEN. A diverse set of application scenarios is presented to demonstrate the promises of LLaVA-Interactive and to inspire future research in multimodal interactive systems.

Accurate and generalizable object segmentation in ultrasound imaging remains a significant challenge due to anatomical variability, diverse imaging protocols, and limited annotated data. In this study, we propose a prompt-driven vision-language model (VLM) that integrates Grounding DINO with SAM2 to enable object segmentation across multiple ultrasound organs. A total of 18 public ultrasound datasets, encompassing the breast, thyroid, liver, prostate, kidney, and paraspinal muscle, were utilized. These datasets were divided into 15 for fine-tuning and validation of Grounding DINO using Low Rank Adaptation (LoRA) to the ultrasound domain, and 3 were held out entirely for testing to evaluate performance in unseen distributions. Comprehensive experiments demonstrate that our approach outperforms state-of-the-art segmentation methods, including UniverSeg, MedSAM, MedCLIP-SAM, BiomedParse, and SAMUS on most seen datasets while maintaining strong performance on unseen datasets without additional fine-tuning. These results underscore the promise of VLMs in scalable and robust ultrasound image analysis, reducing dependence on large, organ-specific annotated datasets. We will publish our code on code.sonography.ai after acceptance.

Audio-visual segmentation aims to separate sounding objects from videos by predicting pixel-level masks based on audio signals. Existing methods primarily concentrate on closed-set scenarios and direct audio-visual alignment and fusion, which limits their capability to generalize to new, unseen situations. In this paper, we propose OpenAVS, a novel training-free language-based approach that, for the first time, effectively aligns audio and visual modalities using text as a proxy for open-vocabulary Audio-Visual Segmentation (AVS). Equipped with multimedia foundation models, OpenAVS directly infers masks through 1) audio-to-text prompt generation, 2) LLM-guided prompt translation, and 3) text-to-visual sounding object segmentation. The objective of OpenAVS is to establish a simple yet flexible architecture that relies on the most appropriate foundation models by fully leveraging their capabilities to enable more effective knowledge transfer to the downstream AVS task. Moreover, we present a model-agnostic framework OpenAVS-ST that enables the integration of OpenAVS with any advanced supervised AVS model via pseudo-label based self-training. This approach enhances performance by effectively utilizing large-scale unlabeled data when available. Comprehensive experiments on three benchmark datasets demonstrate the superior performance of OpenAVS. It surpasses existing unsupervised, zero-shot, and few-shot AVS methods by a significant margin, achieving absolute performance gains of approximately 9.4% and 10.9% in mIoU and F-score, respectively, in challenging scenarios.

The Segment Anything Model (SAM) has recently gained popularity in the field of image segmentation due to its impressive capabilities in various segmentation tasks and its prompt-based interface. However, recent studies and individual experiments have shown that SAM underperforms in medical image segmentation, since the lack of the medical specific knowledge. This raises the question of how to enhance SAM's segmentation capability for medical images. In this paper, instead of fine-tuning the SAM model, we propose the Medical SAM Adapter (Med-SA), which incorporates domain-specific medical knowledge into the segmentation model using a light yet effective adaptation technique. In Med-SA, we propose Space-Depth Transpose (SD-Trans) to adapt 2D SAM to 3D medical images and Hyper-Prompting Adapter (HyP-Adpt) to achieve prompt-conditioned adaptation. We conduct comprehensive evaluation experiments on 17 medical image segmentation tasks across various image modalities. Med-SA outperforms several state-of-the-art (SOTA) medical image segmentation methods, while updating only 2\% of the parameters. Our code is released at https://github.com/KidsWithTokens/Medical-SAM-Adapter.

The recent Segment Anything Model (SAM) 2 has demonstrated remarkable foundational competence in semantic segmentation, with its memory mechanism and mask decoder further addressing challenges in video tracking and object occlusion, thereby achieving superior results in interactive segmentation for both images and videos. Building upon our previous empirical studies, we further explore the zero-shot segmentation performance of SAM 2 in robot-assisted surgery based on prompts, alongside its robustness against real-world corruption. For static images, we employ two forms of prompts: 1-point and bounding box, while for video sequences, the 1-point prompt is applied to the initial frame. Through extensive experimentation on the MICCAI EndoVis 2017 and EndoVis 2018 benchmarks, SAM 2, when utilizing bounding box prompts, outperforms state-of-the-art (SOTA) methods in comparative evaluations. The results with point prompts also exhibit a substantial enhancement over SAM's capabilities, nearing or even surpassing existing unprompted SOTA methodologies. Besides, SAM 2 demonstrates improved inference speed and less performance degradation against various image corruption. Although slightly unsatisfactory results remain in specific edges or regions, SAM 2's robust adaptability to 1-point prompts underscores its potential for downstream surgical tasks with limited prompt requirements.

Foundation segmentation models, while powerful, pose a significant risk: they enable users to effortlessly extract any objects from any digital content with a single click, potentially leading to copyright infringement or malicious misuse. To mitigate this risk, we introduce a new task "Anything Unsegmentable" to grant any image "the right to be unsegmented". The ambitious pursuit of the task is to achieve highly transferable adversarial attacks against all prompt-based segmentation models, regardless of model parameterizations and prompts. We highlight the non-transferable and heterogeneous nature of prompt-specific adversarial noises. Our approach focuses on disrupting image encoder features to achieve prompt-agnostic attacks. Intriguingly, targeted feature attacks exhibit better transferability compared to untargeted ones, suggesting the optimal update direction aligns with the image manifold. Based on the observations, we design a novel attack named Unsegment Anything by Simulating Deformation (UAD). Our attack optimizes a differentiable deformation function to create a target deformed image, which alters structural information while preserving achievable feature distance by adversarial example. Extensive experiments verify the effectiveness of our approach, compromising a variety of promptable segmentation models with different architectures and prompt interfaces. We release the code at https://github.com/jiahaolu97/anything-unsegmentable.

We tackle the challenge of open-vocabulary segmentation, where we need to identify objects from a wide range of categories in different environments, using text prompts as our input. To overcome this challenge, existing methods often use multi-modal models like CLIP, which combine image and text features in a shared embedding space to bridge the gap between limited and extensive vocabulary recognition, resulting in a two-stage approach: In the first stage, a mask generator takes an input image to generate mask proposals, and the in the second stage the target mask is picked based on the query. However, the expected target mask may not exist in the generated mask proposals, which leads to an unexpected output mask. In our work, we propose a novel approach named Prompt-guided Mask Proposal (PMP) where the mask generator takes the input text prompts and generates masks guided by these prompts. Compared with mask proposals generated without input prompts, masks generated by PMP are better aligned with the input prompts. To realize PMP, we designed a cross-attention mechanism between text tokens and query tokens which is capable of generating prompt-guided mask proposals after each decoding. We combined our PMP with several existing works employing a query-based segmentation backbone and the experiments on five benchmark datasets demonstrate the effectiveness of this approach, showcasing significant improvements over the current two-stage models (1% ~ 3% absolute performance gain in terms of mIOU). The steady improvement in performance across these benchmarks indicates the effective generalization of our proposed lightweight prompt-aware method.

Zero- and few-shot visual anomaly segmentation relies on powerful vision-language models that detect unseen anomalies using manually designed textual prompts. However, visual representations are inherently independent of language. In this paper, we explore the potential of a pure visual foundation model as an alternative to widely used vision-language models for universal visual anomaly segmentation. We present a novel paradigm that unifies anomaly segmentation into change segmentation. This paradigm enables us to leverage large-scale synthetic image pairs, featuring object-level and local region changes, derived from existing image datasets, which are independent of target anomaly datasets. We propose a one-prompt Meta-learning framework for Universal Anomaly Segmentation (MetaUAS) that is trained on this synthetic dataset and then generalizes well to segment any novel or unseen visual anomalies in the real world. To handle geometrical variations between prompt and query images, we propose a soft feature alignment module that bridges paired-image change perception and single-image semantic segmentation. This is the first work to achieve universal anomaly segmentation using a pure vision model without relying on special anomaly detection datasets and pre-trained visual-language models. Our method effectively and efficiently segments any anomalies with only one normal image prompt and enjoys training-free without guidance from language. Our MetaUAS significantly outperforms previous zero-shot, few-shot, and even full-shot anomaly segmentation methods. The code and pre-trained models are available at https://github.com/gaobb/MetaUAS.

The recent success of CLIP has demonstrated promising results in zero-shot semantic segmentation by transferring muiltimodal knowledge to pixel-level classification. However, leveraging pre-trained CLIP knowledge to closely align text embeddings with pixel embeddings still has limitations in existing approaches. To address this issue, we propose OTSeg, a novel multimodal attention mechanism aimed at enhancing the potential of multiple text prompts for matching associated pixel embeddings. We first propose Multi-Prompts Sinkhorn (MPS) based on the Optimal Transport (OT) algorithm, which leads multiple text prompts to selectively focus on various semantic features within image pixels. Moreover, inspired by the success of Sinkformers in unimodal settings, we introduce the extension of MPS, called Multi-Prompts Sinkhorn Attention (MPSA) , which effectively replaces cross-attention mechanisms within Transformer framework in multimodal settings. Through extensive experiments, we demonstrate that OTSeg achieves state-of-the-art (SOTA) performance with significant gains on Zero-Shot Semantic Segmentation (ZS3) tasks across three benchmark datasets.

Recent advancements in multimodal vision models have highlighted limitations in late-stage feature fusion and suboptimal query selection for hybrid prompts open-world segmentation, alongside constraints from caption-derived vocabularies. To address these challenges, we propose Prompt-DINO, a text-guided visual Prompt DINO framework featuring three key innovations. First, we introduce an early fusion mechanism that unifies text/visual prompts and backbone features at the initial encoding stage, enabling deeper cross-modal interactions to resolve semantic ambiguities. Second, we design order-aligned query selection for DETR-based architectures, explicitly optimizing the structural alignment between text and visual queries during decoding to enhance semantic-spatial consistency. Third, we develop a generative data engine powered by the Recognize Anything via Prompting (RAP) model, which synthesizes 0.5B diverse training instances through a dual-path cross-verification pipeline, reducing label noise by 80.5% compared to conventional approaches. Extensive experiments demonstrate that Prompt-DINO achieves state-of-the-art performance on open-world detection benchmarks while significantly expanding semantic coverage beyond fixed-vocabulary constraints. Our work establishes a new paradigm for scalable multimodal detection and data generation in open-world scenarios. Data&Code are available at https://github.com/WeChatCV/WeVisionOne.

Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps requires carefully curated post-processing, which is error-prone and parameter-sensitive. Recently, the Segment Anything Model (SAM) has earned huge attention in medical image segmentation, owing to its impressive generalization ability and promptable property. Nevertheless, its potential on nucleus instance segmentation remains largely underexplored. In this paper, we present a novel prompt-driven framework that consists of a nucleus prompter and SAM for automatic nucleus instance segmentation. Specifically, the prompter learns to generate a unique point prompt for each nucleus while the SAM is fine-tuned to output the corresponding mask for the prompted nucleus. Furthermore, we propose the inclusion of adjacent nuclei as negative prompts to enhance the model's capability to identify overlapping nuclei. Without complicated post-processing, our proposed method sets a new state-of-the-art performance on three challenging benchmarks. Code is available at github.com/windygoo/PromptNucSeg

Audio-guided Video Object Segmentation (A-VOS) and Referring Video Object Segmentation (R-VOS) are two highly-related tasks, which both aim to segment specific objects from video sequences according to user-provided expression prompts. However, due to the challenges in modeling representations for different modalities, contemporary methods struggle to strike a balance between interaction flexibility and high-precision localization and segmentation. In this paper, we address this problem from two perspectives: the alignment representation of audio and text and the deep interaction among audio, text, and visual features. First, we propose a universal architecture, the Expression Prompt Collaboration Transformer, herein EPCFormer. Next, we propose an Expression Alignment (EA) mechanism for audio and text expressions. By introducing contrastive learning for audio and text expressions, the proposed EPCFormer realizes comprehension of the semantic equivalence between audio and text expressions denoting the same objects. Then, to facilitate deep interactions among audio, text, and video features, we introduce an Expression-Visual Attention (EVA) mechanism. The knowledge of video object segmentation in terms of the expression prompts can seamlessly transfer between the two tasks by deeply exploring complementary cues between text and audio. Experiments on well-recognized benchmarks demonstrate that our universal EPCFormer attains state-of-the-art results on both tasks. The source code of EPCFormer will be made publicly available at https://github.com/lab206/EPCFormer.

Prompt engineering has shown remarkable success with large language models, yet its systematic exploration in computer vision remains limited. In semantic segmentation, both textual and visual prompts offer distinct advantages: textual prompts through open-vocabulary methods allow segmentation of arbitrary categories, while visual reference prompts provide intuitive reference examples. However, existing benchmarks evaluate these modalities in isolation, without direct comparison under identical conditions. We present Show or Tell (SoT), a novel benchmark specifically designed to evaluate both visual and textual prompts for semantic segmentation across 14 datasets spanning 7 diverse domains (common scenes, urban, food, waste, parts, tools, and land-cover). We evaluate 5 open-vocabulary methods and 4 visual reference prompt approaches, adapting the latter to handle multi-class segmentation through a confidence-based mask merging strategy. Our extensive experiments reveal that open-vocabulary methods excel with common concepts easily described by text but struggle with complex domains like tools, while visual reference prompt methods achieve good average results but exhibit high variability depending on the input prompt. Through comprehensive quantitative and qualitative analysis, we identify the strengths and weaknesses of both prompting modalities, providing valuable insights to guide future research in vision foundation models for segmentation tasks.

The recently introduced Segment Anything Model (SAM) combines a clever architecture and large quantities of training data to obtain remarkable image segmentation capabilities. However, it fails to reproduce such results for Out-Of-Distribution (OOD) domains such as medical images. Moreover, while SAM is conditioned on either a mask or a set of points, it may be desirable to have a fully automatic solution. In this work, we replace SAM's conditioning with an encoder that operates on the same input image. By adding this encoder and without further fine-tuning SAM, we obtain state-of-the-art results on multiple medical images and video benchmarks. This new encoder is trained via gradients provided by a frozen SAM. For inspecting the knowledge within it, and providing a lightweight segmentation solution, we also learn to decode it into a mask by a shallow deconvolution network.

Foundation models like the Segment Anything Model (SAM) have significantly advanced promptable image segmentation in computer vision. However, extending these capabilities to videos presents substantial challenges, particularly in ensuring precise and temporally consistent mask propagation in dynamic scenes. SAM 2 attempts to address this by training a model on massive image and video data from scratch to learn complex spatiotemporal associations, resulting in huge training costs that hinder research and practical deployment. In this paper, we introduce SAM-I2V, an effective image-to-video upgradation method for cultivating a promptable video segmentation (PVS) model. Our approach strategically upgrades the pre-trained SAM to support PVS, significantly reducing training complexity and resource requirements. To achieve this, we introduce three key innovations: (i) an image-to-video feature extraction upgrader built upon SAM's static image encoder to enable spatiotemporal video perception, (ii) a memory filtering strategy that selects the most relevant past frames for more effective utilization of historical information, and (iii) a memory-as-prompt mechanism leveraging object memory to ensure temporally consistent mask propagation in dynamic scenes. Comprehensive experiments demonstrate that our method achieves over 90% of SAM 2's performance while using only 0.2% of its training cost. Our work presents a resource-efficient pathway to PVS, lowering barriers for further research in PVS model design and enabling broader applications and advancements in the field. Code and model are available at: https://github.com/showlab/SAM-I2V.

Current closed-set instance segmentation models rely on pre-defined class labels for each mask during training and evaluation, largely limiting their ability to detect novel objects. Open-world instance segmentation (OWIS) models address this challenge by detecting unknown objects in a class-agnostic manner. However, previous OWIS approaches completely erase category information during training to keep the model's ability to generalize to unknown objects. In this work, we propose a novel training mechanism termed SegPrompt that uses category information to improve the model's class-agnostic segmentation ability for both known and unknown categories. In addition, the previous OWIS training setting exposes the unknown classes to the training set and brings information leakage, which is unreasonable in the real world. Therefore, we provide a new open-world benchmark closer to a real-world scenario by dividing the dataset classes into known-seen-unseen parts. For the first time, we focus on the model's ability to discover objects that never appear in the training set images. Experiments show that SegPrompt can improve the overall and unseen detection performance by 5.6% and 6.1% in AR on our new benchmark without affecting the inference efficiency. We further demonstrate the effectiveness of our method on existing cross-dataset transfer and strongly supervised settings, leading to 5.5% and 12.3% relative improvement.

Despite that the segment anything model (SAM) achieved impressive results on general-purpose semantic segmentation with strong generalization ability on daily images, its demonstrated performance on medical image segmentation is less precise and not stable, especially when dealing with tumor segmentation tasks that involve objects of small sizes, irregular shapes, and low contrast. Notably, the original SAM architecture is designed for 2D natural images, therefore would not be able to extract the 3D spatial information from volumetric medical data effectively. In this paper, we propose a novel adaptation method for transferring SAM from 2D to 3D for promptable medical image segmentation. Through a holistically designed scheme for architecture modification, we transfer the SAM to support volumetric inputs while retaining the majority of its pre-trained parameters for reuse. The fine-tuning process is conducted in a parameter-efficient manner, wherein most of the pre-trained parameters remain frozen, and only a few lightweight spatial adapters are introduced and tuned. Regardless of the domain gap between natural and medical data and the disparity in the spatial arrangement between 2D and 3D, the transformer trained on natural images can effectively capture the spatial patterns present in volumetric medical images with only lightweight adaptations. We conduct experiments on four open-source tumor segmentation datasets, and with a single click prompt, our model can outperform domain state-of-the-art medical image segmentation models on 3 out of 4 tasks, specifically by 8.25%, 29.87%, and 10.11% for kidney tumor, pancreas tumor, colon cancer segmentation, and achieve similar performance for liver tumor segmentation. We also compare our adaptation method with existing popular adapters, and observed significant performance improvement on most datasets.

Text-to-image generation models~(e.g., Stable Diffusion) have achieved significant advancements, enabling the creation of high-quality and realistic images based on textual descriptions. Prompt inversion, the task of identifying the textual prompt used to generate a specific artifact, holds significant potential for applications including data attribution, model provenance, and watermarking validation. Recent studies introduced a delayed projection scheme to optimize for prompts representative of the vocabulary space, though challenges in semantic fluency and efficiency remain. Advanced image captioning models or visual large language models can generate highly interpretable prompts, but they often lack in image similarity. In this paper, we propose a prompt inversion technique called \sys for text-to-image diffusion models, which includes initializing embeddings using a pre-trained image captioning model, refining them through reverse-engineering in the latent space, and converting them to texts using an embedding-to-text model. Our experiments on the widely-used datasets, such as MS COCO, LAION, and Flickr, show that our method outperforms existing methods in terms of image similarity, textual alignment, prompt interpretability and generalizability. We further illustrate the application of our generated prompts in tasks such as cross-concept image synthesis, concept manipulation, evolutionary multi-concept generation and unsupervised segmentation.

Few-shot segmentation is the problem of learning to identify specific types of objects (e.g., airplanes) in images from a small set of labeled reference images. The current state of the art is driven by resource-intensive construction of models for every new domain-specific application. Such models must be trained on enormous labeled datasets of unrelated objects (e.g., cars, trains, animals) so that their ``knowledge'' can be transferred to new types of objects. In this paper, we show how to leverage existing vision foundation models (VFMs) to reduce the incremental cost of creating few-shot segmentation models for new domains. Specifically, we introduce SAMIC, a small network that learns how to prompt VFMs in order to segment new types of objects in domain-specific applications. SAMIC enables any task to be approached as a few-shot learning problem. At 2.6 million parameters, it is 94% smaller than the leading models (e.g., having ResNet 101 backbone with 45+ million parameters). Even using 1/5th of the training data provided by one-shot benchmarks, SAMIC is competitive with, or sets the state of the art, on a variety of few-shot and semantic segmentation datasets including COCO-20^i, Pascal-5^i, PerSeg, FSS-1000, and NWPU VHR-10.

Background: We evaluate SAM 2 for surgical scene understanding by examining its semantic segmentation capabilities for organs/tissues both in zero-shot scenarios and after fine-tuning. Methods: We utilized five public datasets to evaluate and fine-tune SAM 2 for segmenting anatomical tissues in surgical videos/images. Fine-tuning was applied to the image encoder and mask decoder. We limited training subsets from 50 to 400 samples per class to better model real-world constraints with data acquisition. The impact of dataset size on fine-tuning performance was evaluated with weighted mean Dice coefficient (WMDC), and the results were also compared against previously reported state-of-the-art (SOTA) results. Results: SurgiSAM 2, a fine-tuned SAM 2 model, demonstrated significant improvements in segmentation performance, achieving a 17.9% relative WMDC gain compared to the baseline SAM 2. Increasing prompt points from 1 to 10 and training data scale from 50/class to 400/class enhanced performance; the best WMDC of 0.92 on the validation subset was achieved with 10 prompt points and 400 samples per class. On the test subset, this model outperformed prior SOTA methods in 24/30 (80%) of the classes with a WMDC of 0.91 using 10-point prompts. Notably, SurgiSAM 2 generalized effectively to unseen organ classes, achieving SOTA on 7/9 (77.8%) of them. Conclusion: SAM 2 achieves remarkable zero-shot and fine-tuned performance for surgical scene segmentation, surpassing prior SOTA models across several organ classes of diverse datasets. This suggests immense potential for enabling automated/semi-automated annotation pipelines, thereby decreasing the burden of annotations facilitating several surgical applications.

This paper presents the first study on adapting the visual in-context learning (V-ICL) paradigm to optical character recognition tasks, specifically focusing on text removal and segmentation. Most existing V-ICL generalists employ a reasoning-as-reconstruction approach: they turn to using a straightforward image-label compositor as the prompt and query input, and then masking the query label to generate the desired output. This direct prompt confines the model to a challenging single-step reasoning process. To address this, we propose a task-chaining compositor in the form of image-removal-segmentation, providing an enhanced prompt that elicits reasoning with enriched intermediates. Additionally, we introduce context-aware aggregation, integrating the chained prompt pattern into the latent query representation, thereby strengthening the model's in-context reasoning. We also consider the issue of visual heterogeneity, which complicates the selection of homogeneous demonstrations in text recognition. Accordingly, this is effectively addressed through a simple self-prompting strategy, preventing the model's in-context learnability from devolving into specialist-like, context-free inference. Collectively, these insights culminate in our ConText model, which achieves new state-of-the-art across both in- and out-of-domain benchmarks. The code is available at https://github.com/Ferenas/ConText.

Zero-shot and prompt-based technologies capitalized on using frequently occurring images to transform visual reasoning tasks, which explains why such technologies struggle with valuable yet scarce scientific image sets. In this work, we propose Zenesis, a comprehensive no-code interactive platform designed to minimize barriers posed by data readiness for scientific images. We develop lightweight multi-modal adaptation techniques that enable zero-shot operation on raw scientific data, along with human-in-the-loop refinement and heuristic-based temporal enhancement options. We demonstrate the performance of our approach through comprehensive comparison and validation on challenging Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) data of catalyst-loaded membranes. Zenesis significantly outperforms baseline methods, achieving an average accuracy of 0.947, an Intersection over Union (IOU) of 0.858, and a Dice score of 0.923 for amorphous catalyst samples and accuracy of 0.987, an IOU of 0.857, and a Dice score of 0.923 for crystalline samples. These results mark a substantial improvement over traditional methods like Otsu thresholding and even advanced models like Segment Anything Model (SAM) when used in isolation. Our results demonstrate that Zenesis is a powerful tool for scientific applications, particularly in fields where high-quality annotated datasets are unavailable, accelerating accurate analysis of experimental imaging.

Recent advancements in prompt-based medical image segmentation have enabled clinicians to identify tumors using simple input like bounding boxes or text prompts. However, existing methods face challenges when doctors need to interact through natural language or when position reasoning is required - understanding spatial relationships between anatomical structures and pathologies. We present PRS-Med, a framework that integrates vision-language models with segmentation capabilities to generate both accurate segmentation masks and corresponding spatial reasoning outputs. Additionally, we introduce the MMRS dataset (Multimodal Medical in Positional Reasoning Segmentation), which provides diverse, spatially-grounded question-answer pairs to address the lack of position reasoning data in medical imaging. PRS-Med demonstrates superior performance across six imaging modalities (CT, MRI, X-ray, ultrasound, endoscopy, RGB), significantly outperforming state-of-the-art methods in both segmentation accuracy and position reasoning. Our approach enables intuitive doctor-system interaction through natural language, facilitating more efficient diagnoses. Our dataset pipeline, model, and codebase will be released to foster further research in spatially-aware multimodal reasoning for medical applications.

Limited labeled data makes it hard to train models from scratch in medical domain, and an important paradigm is pre-training and then fine-tuning. Large pre-trained models contain rich representations, which can be adapted to downstream medical tasks. However, existing methods either tune all the parameters or the task-specific layers of the pre-trained models, ignoring the input variations of medical images, and thus they are not efficient or effective. In this work, we aim to study parameter-efficient fine-tuning (PEFT) for medical image analysis, and propose a dynamic visual prompt tuning method, named DVPT. It can extract knowledge beneficial to downstream tasks from large models with a few trainable parameters. Firstly, the frozen features are transformed by an lightweight bottleneck layer to learn the domain-specific distribution of downstream medical tasks, and then a few learnable visual prompts are used as dynamic queries and then conduct cross-attention with the transformed features, attempting to acquire sample-specific knowledge that are suitable for each sample. Finally, the features are projected to original feature dimension and aggregated with the frozen features. This DVPT module can be shared between different Transformer layers, further reducing the trainable parameters. To validate DVPT, we conduct extensive experiments with different pre-trained models on medical classification and segmentation tasks. We find such PEFT method can not only efficiently adapt the pre-trained models to the medical domain, but also brings data efficiency with partial labeled data. For example, with 0.5\% extra trainable parameters, our method not only outperforms state-of-the-art PEFT methods, even surpasses the full fine-tuning by more than 2.20\% Kappa score on medical classification task. It can saves up to 60\% labeled data and 99\% storage cost of ViT-B/16.

Recent advances in Large Multi-modal Models (LMMs) have demonstrated their remarkable success as general-purpose multi-modal assistants, with particular focuses on holistic image- and video-language understanding. Conversely, less attention has been given to scaling fine-grained pixel-level understanding capabilities, where the models are expected to realize pixel-level alignment between visual signals and language semantics. Some previous studies have applied LMMs to related tasks such as region-level captioning and referring expression segmentation. However, these models are limited to performing either referring or segmentation tasks independently and fail to integrate these fine-grained perception capabilities into visual reasoning. To bridge this gap, we propose UniPixel, a large multi-modal model capable of flexibly comprehending visual prompt inputs and generating mask-grounded responses. Our model distinguishes itself by seamlessly integrating pixel-level perception with general visual understanding capabilities. Specifically, UniPixel processes visual prompts and generates relevant masks on demand, and performs subsequent reasoning conditioning on these intermediate pointers during inference, thereby enabling fine-grained pixel-level reasoning. The effectiveness of our approach has been verified on 10 benchmarks across a diverse set of tasks, including pixel-level referring/segmentation and object-centric understanding in images/videos. A novel PixelQA task that jointly requires referring, segmentation, and question answering is also designed to verify the flexibility of our method.

This paper addresses text-supervised semantic segmentation, aiming to learn a model capable of segmenting arbitrary visual concepts within images by using only image-text pairs without dense annotations. Existing methods have demonstrated that contrastive learning on image-text pairs effectively aligns visual segments with the meanings of texts. We notice that there is a discrepancy between text alignment and semantic segmentation: A text often consists of multiple semantic concepts, whereas semantic segmentation strives to create semantically homogeneous segments. To address this issue, we propose a novel framework, Image-Text Co-Decomposition (CoDe), where the paired image and text are jointly decomposed into a set of image regions and a set of word segments, respectively, and contrastive learning is developed to enforce region-word alignment. To work with a vision-language model, we present a prompt learning mechanism that derives an extra representation to highlight an image segment or a word segment of interest, with which more effective features can be extracted from that segment. Comprehensive experimental results demonstrate that our method performs favorably against existing text-supervised semantic segmentation methods on six benchmark datasets.

Medical imaging is crucial for diagnosing a patient's health condition, and accurate segmentation of these images is essential for isolating regions of interest to ensure precise diagnosis and treatment planning. Existing methods primarily rely on bounding boxes or point-based prompts, while few have explored text-related prompts, despite clinicians often describing their observations and instructions in natural language. To address this gap, we first propose a RAG-based free-form text prompt generator, that leverages the domain corpus to generate diverse and realistic descriptions. Then, we introduce FLanS, a novel medical image segmentation model that handles various free-form text prompts, including professional anatomy-informed queries, anatomy-agnostic position-driven queries, and anatomy-agnostic size-driven queries. Additionally, our model also incorporates a symmetry-aware canonicalization module to ensure consistent, accurate segmentations across varying scan orientations and reduce confusion between the anatomical position of an organ and its appearance in the scan. FLanS is trained on a large-scale dataset of over 100k medical images from 7 public datasets. Comprehensive experiments demonstrate the model's superior language understanding and segmentation precision, along with a deep comprehension of the relationship between them, outperforming SOTA baselines on both in-domain and out-of-domain datasets.

Crowd counting has achieved significant progress by training regressors to predict instance positions. In heavily crowded scenarios, however, regressors are challenged by uncontrollable annotation variance, which causes density map bias and context information inaccuracy. In this study, we propose mutual prompt learning (mPrompt), which leverages a regressor and a segmenter as guidance for each other, solving bias and inaccuracy caused by annotation variance while distinguishing foreground from background. In specific, mPrompt leverages point annotations to tune the segmenter and predict pseudo head masks in a way of point prompt learning. It then uses the predicted segmentation masks, which serve as spatial constraint, to rectify biased point annotations as context prompt learning. mPrompt defines a way of mutual information maximization from prompt learning, mitigating the impact of annotation variance while improving model accuracy. Experiments show that mPrompt significantly reduces the Mean Average Error (MAE), demonstrating the potential to be general framework for down-stream vision tasks.

Recent works on Generalized Referring Expression Segmentation (GRES) struggle with handling complex expressions referring to multiple distinct objects. This is because these methods typically employ an end-to-end foreground-background segmentation and lack a mechanism to explicitly differentiate and associate different object instances to the text query. To this end, we propose InstAlign, a method that incorporates object-level reasoning into the segmentation process. Our model leverages both text and image inputs to extract a set of object-level tokens that capture both the semantic information in the input prompt and the objects within the image. By modeling the text-object alignment via instance-level supervision, each token uniquely represents an object segment in the image, while also aligning with relevant semantic information from the text. Extensive experiments on the gRefCOCO and Ref-ZOM benchmarks demonstrate that our method significantly advances state-of-the-art performance, setting a new standard for precise and flexible GRES.

This paper presents a parameter-efficient prompt tuning method, named PPT, to adapt a large multi-modal model for 3D point cloud understanding. Existing strategies are quite expensive in computation and storage, and depend on time-consuming prompt engineering. We address the problems from three aspects. Firstly, a PromptLearner module is devised to replace hand-crafted prompts with learnable contexts to automate the prompt tuning process. Then, we lock the pre-trained backbone instead of adopting the full fine-tuning paradigm to substantially improve the parameter efficiency. Finally, a lightweight PointAdapter module is arranged near target tasks to enhance prompt tuning for 3D point cloud understanding. Comprehensive experiments are conducted to demonstrate the superior parameter and data efficiency of the proposed method.Meanwhile, we obtain new records on 4 public datasets and multiple 3D tasks, i.e., point cloud recognition, few-shot learning, and part segmentation. The implementation is available at https://github.com/auniquesun/PPT.

Recent approaches have shown that large-scale vision-language models such as CLIP can improve semantic segmentation performance. These methods typically aim for pixel-level vision-language alignment, but often rely on low resolution image features from CLIP, resulting in class ambiguities along boundaries. Moreover, the global scene representations in CLIP text embeddings do not directly correlate with the local and detailed pixel-level features, making meaningful alignment more difficult. To address these limitations, we introduce MTA-CLIP, a novel framework employing mask-level vision-language alignment. Specifically, we first propose Mask-Text Decoder that enhances the mask representations using rich textual data with the CLIP language model. Subsequently, it aligns mask representations with text embeddings using Mask-to-Text Contrastive Learning. Furthermore, we introduce MaskText Prompt Learning, utilizing multiple context-specific prompts for text embeddings to capture diverse class representations across masks. Overall, MTA-CLIP achieves state-of-the-art, surpassing prior works by an average of 2.8% and 1.3% on on standard benchmark datasets, ADE20k and Cityscapes, respectively.

Point cloud segmentation is a fundamental task in 3D vision that serves a wide range of applications. Although great progresses have been made these years, its practical usability is still limited by the availability of training data. Existing approaches cannot make full use of multiple datasets on hand due to the label mismatch among different datasets. In this paper, we propose a principled approach that supports learning from heterogeneous datasets with different label sets. Our idea is to utilize a pre-trained language model to embed discrete labels to a continuous latent space with the help of their label names. This unifies all labels of different datasets, so that joint training is doable. Meanwhile, classifying points in the continuous 3D space by their vocabulary tokens significantly increase the generalization ability of the model in comparison with existing approaches that have fixed decoder architecture. Besides, we also integrate prompt learning in our framework to alleviate data shifts among different data sources. Extensive experiments demonstrate that our model outperforms the state-of-the-art by a large margin.

This work proposes POMP, a prompt pre-training method for vision-language models. Being memory and computation efficient, POMP enables the learned prompt to condense semantic information for a rich set of visual concepts with over twenty-thousand classes. Once pre-trained, the prompt with a strong transferable ability can be directly plugged into a variety of visual recognition tasks including image classification, semantic segmentation, and object detection, to boost recognition performances in a zero-shot manner. Empirical evaluation shows that POMP achieves state-of-the-art performances on 21 downstream datasets, e.g., 67.0% average accuracy on 10 classification dataset (+3.1% compared to CoOp) and 84.4 hIoU on open-vocabulary Pascal VOC segmentation (+6.9 compared to ZSSeg).

Recently, open-vocabulary learning has emerged to accomplish segmentation for arbitrary categories of text-based descriptions, which popularizes the segmentation system to more general-purpose application scenarios. However, existing methods devote to designing specialized architectures or parameters for specific segmentation tasks. These customized design paradigms lead to fragmentation between various segmentation tasks, thus hindering the uniformity of segmentation models. Hence in this paper, we propose FreeSeg, a generic framework to accomplish Unified, Universal and Open-Vocabulary Image Segmentation. FreeSeg optimizes an all-in-one network via one-shot training and employs the same architecture and parameters to handle diverse segmentation tasks seamlessly in the inference procedure. Additionally, adaptive prompt learning facilitates the unified model to capture task-aware and category-sensitive concepts, improving model robustness in multi-task and varied scenarios. Extensive experimental results demonstrate that FreeSeg establishes new state-of-the-art results in performance and generalization on three segmentation tasks, which outperforms the best task-specific architectures by a large margin: 5.5% mIoU on semantic segmentation, 17.6% mAP on instance segmentation, 20.1% PQ on panoptic segmentation for the unseen class on COCO.

Domain adaptation has been vastly investigated in computer vision but still requires access to target images at train time, which might be intractable in some uncommon conditions. In this paper, we propose the task of `Prompt-driven Zero-shot Domain Adaptation', where we adapt a model trained on a source domain using only a general description in natural language of the target domain, i.e., a prompt. First, we leverage a pretrained contrastive vision-language model (CLIP) to optimize affine transformations of source features, steering them towards the target text embedding while preserving their content and semantics. To achieve this, we propose Prompt-driven Instance Normalization (PIN). Second, we show that these prompt-driven augmentations can be used to perform zero-shot domain adaptation for semantic segmentation. Experiments demonstrate that our method significantly outperforms CLIP-based style transfer baselines on several datasets for the downstream task at hand, even surpassing one-shot unsupervised domain adaptation. A similar boost is observed on object detection and image classification. The code is available at https://github.com/astra-vision/PODA .

Video Object Segmentation (VOS) is foundational to numerous computer vision applications, including surveillance, autonomous driving, robotics and generative video editing. However, existing VOS models often struggle with precise mask delineation, deformable objects, topologically transforming objects, tracking drift and long video sequences. In this paper, we introduce HQ-SMem, for High Quality video segmentation and tracking using Smart Memory, a novel method that enhances the performance of VOS base models by addressing these limitations. Our approach incorporates three key innovations: (i) leveraging SAM with High-Quality masks (SAM-HQ) alongside appearance-based candidate-selection to refine coarse segmentation masks, resulting in improved object boundaries; (ii) implementing a dynamic smart memory mechanism that selectively stores relevant key frames while discarding redundant ones, thereby optimizing memory usage and processing efficiency for long-term videos; and (iii) dynamically updating the appearance model to effectively handle complex topological object variations and reduce drift throughout the video. These contributions mitigate several limitations of existing VOS models including, coarse segmentations that mix-in background pixels, fixed memory update schedules, brittleness to drift and occlusions, and prompt ambiguity issues associated with SAM. Extensive experiments conducted on multiple public datasets and state-of-the-art base trackers demonstrate that our method consistently ranks among the top two on VOTS and VOTSt 2024 datasets. Moreover, HQ-SMem sets new benchmarks on Long Video Dataset and LVOS, showcasing its effectiveness in challenging scenarios characterized by complex multi-object dynamics over extended temporal durations.

Prompt injection attacks manipulate large language models (LLMs) by misleading them to deviate from the original input instructions and execute maliciously injected instructions, because of their instruction-following capabilities and inability to distinguish between the original input instructions and maliciously injected instructions. To defend against such attacks, recent studies have developed various detection mechanisms. If we restrict ourselves specifically to works which perform detection rather than direct defense, most of them focus on direct prompt injection attacks, while there are few works for the indirect scenario, where injected instructions are indirectly from external tools, such as a search engine. Moreover, current works mainly investigate injection detection methods and pay less attention to the post-processing method that aims to mitigate the injection after detection. In this paper, we investigate the feasibility of detecting and removing indirect prompt injection attacks, and we construct a benchmark dataset for evaluation. For detection, we assess the performance of existing LLMs and open-source detection models, and we further train detection models using our crafted training datasets. For removal, we evaluate two intuitive methods: (1) the segmentation removal method, which segments the injected document and removes parts containing injected instructions, and (2) the extraction removal method, which trains an extraction model to identify and remove injected instructions.

Current prevailing Video Object Segmentation (VOS) methods usually perform dense matching between the current and reference frames after extracting their features. One on hand, the decoupled modeling restricts the targets information propagation only at high-level feature space. On the other hand, the pixel-wise matching leads to a lack of holistic understanding of the targets. To overcome these issues, we propose a unified VOS framework, coined as JointFormer, for joint modeling the three elements of feature, correspondence, and a compressed memory. The core design is the Joint Block, utilizing the flexibility of attention to simultaneously extract feature and propagate the targets information to the current tokens and the compressed memory token. This scheme allows to perform extensive information propagation and discriminative feature learning. To incorporate the long-term temporal targets information, we also devise a customized online updating mechanism for the compressed memory token, which can prompt the information flow along the temporal dimension and thus improve the global modeling capability. Under the design, our method achieves a new state-of-art performance on DAVIS 2017 val/test-dev (89.7% and 87.6%) and YouTube-VOS 2018/2019 val (87.0% and 87.0%) benchmarks, outperforming existing works by a large margin.

Recent advancements in 2D and multimodal models have achieved remarkable success by leveraging large-scale training on extensive datasets. However, extending these achievements to enable free-form interactions and high-level semantic operations with complex 3D/4D scenes remains challenging. This difficulty stems from the limited availability of large-scale, annotated 3D/4D or multi-view datasets, which are crucial for generalizable vision and language tasks such as open-vocabulary and prompt-based segmentation, language-guided editing, and visual question answering (VQA). In this paper, we introduce Feature4X, a universal framework designed to extend any functionality from 2D vision foundation model into the 4D realm, using only monocular video input, which is widely available from user-generated content. The "X" in Feature4X represents its versatility, enabling any task through adaptable, model-conditioned 4D feature field distillation. At the core of our framework is a dynamic optimization strategy that unifies multiple model capabilities into a single representation. Additionally, to the best of our knowledge, Feature4X is the first method to distill and lift the features of video foundation models (e.g. SAM2, InternVideo2) into an explicit 4D feature field using Gaussian Splatting. Our experiments showcase novel view segment anything, geometric and appearance scene editing, and free-form VQA across all time steps, empowered by LLMs in feedback loops. These advancements broaden the scope of agentic AI applications by providing a foundation for scalable, contextually and spatiotemporally aware systems capable of immersive dynamic 4D scene interaction.

Recent vision-language models (e.g., CLIP) have demonstrated remarkable class-generalizable ability to unseen classes in few-shot anomaly segmentation (FSAS), leveraging supervised prompt learning or fine-tuning on seen classes. However, their cross-category generalization largely depends on prior knowledge of real seen anomaly samples. In this paper, we propose a novel framework, namely DictAS, which enables a unified model to detect visual anomalies in unseen object categories without any retraining on the target data, only employing a few normal reference images as visual prompts. The insight behind DictAS is to transfer dictionary lookup capabilities to the FSAS task for unseen classes via self-supervised learning, instead of merely memorizing the normal and abnormal feature patterns from the training set. Specifically, DictAS mainly consists of three components: (1) **Dictionary Construction** - to simulate the index and content of a real dictionary using features from normal reference images. (2) **Dictionary Lookup** - to retrieve queried region features from the dictionary via a sparse lookup strategy. When a query feature cannot be retrieved, it is classified as an anomaly. (3) **Query Discrimination Regularization**- to enhance anomaly discrimination by making abnormal features harder to retrieve from the dictionary. To achieve this, Contrastive Query Constraint and Text Alignment Constraint are further proposed. Extensive experiments on seven public industrial and medical datasets demonstrate that DictAS consistently outperforms state-of-the-art FSAS methods.

Accurate and efficient 3D segmentation is essential for both clinical and research applications. While foundation models like SAM have revolutionized interactive segmentation, their 2D design and domain shift limitations make them ill-suited for 3D medical images. Current adaptations address some of these challenges but remain limited, either lacking volumetric awareness, offering restricted interactivity, or supporting only a small set of structures and modalities. Usability also remains a challenge, as current tools are rarely integrated into established imaging platforms and often rely on cumbersome web-based interfaces with restricted functionality. We introduce nnInteractive, the first comprehensive 3D interactive open-set segmentation method. It supports diverse prompts-including points, scribbles, boxes, and a novel lasso prompt-while leveraging intuitive 2D interactions to generate full 3D segmentations. Trained on 120+ diverse volumetric 3D datasets (CT, MRI, PET, 3D Microscopy, etc.), nnInteractive sets a new state-of-the-art in accuracy, adaptability, and usability. Crucially, it is the first method integrated into widely used image viewers (e.g., Napari, MITK), ensuring broad accessibility for real-world clinical and research applications. Extensive benchmarking demonstrates that nnInteractive far surpasses existing methods, setting a new standard for AI-driven interactive 3D segmentation. nnInteractive is publicly available: https://github.com/MIC-DKFZ/napari-nninteractive (Napari plugin), https://www.mitk.org/MITK-nnInteractive (MITK integration), https://github.com/MIC-DKFZ/nnInteractive (Python backend).

Existing perception models achieve great success by learning from large amounts of labeled data, but they still struggle with open-world scenarios. To alleviate this issue, researchers introduce open-set perception tasks to detect or segment unseen objects in the training set. However, these models require predefined object categories as inputs during inference, which are not available in real-world scenarios. Recently, researchers pose a new and more practical problem, i.e., open-ended object detection, which discovers unseen objects without any object categories as inputs. In this paper, we present VL-SAM, a training-free framework that combines the generalized object recognition model (i.e., Vision-Language Model) with the generalized object localization model (i.e., Segment-Anything Model), to address the open-ended object detection and segmentation task. Without additional training, we connect these two generalized models with attention maps as the prompts. Specifically, we design an attention map generation module by employing head aggregation and a regularized attention flow to aggregate and propagate attention maps across all heads and layers in VLM, yielding high-quality attention maps. Then, we iteratively sample positive and negative points from the attention maps with a prompt generation module and send the sampled points to SAM to segment corresponding objects. Experimental results on the long-tail instance segmentation dataset (LVIS) show that our method surpasses the previous open-ended method on the object detection task and can provide additional instance segmentation masks. Besides, VL-SAM achieves favorable performance on the corner case object detection dataset (CODA), demonstrating the effectiveness of VL-SAM in real-world applications. Moreover, VL-SAM exhibits good model generalization that can incorporate various VLMs and SAMs.

The Segment Anything Model (SAM) has demonstrated outstanding adaptation to medical image segmentation but still faces three major challenges. Firstly, the huge computational costs of SAM limit its real-world applicability. Secondly, SAM depends on manual annotations (e.g., points, boxes) as prompts, which are laborious and impractical in clinical scenarios. Thirdly, SAM handles all segmentation targets equally, which is suboptimal for diverse medical modalities with inherent heterogeneity. To address these issues, we propose an Efficient Self-Prompting SAM for universal medical image segmentation, named ESP-MedSAM. We devise a Multi-Modal Decoupled Knowledge Distillation (MMDKD) strategy to distil common image knowledge and domain-specific medical knowledge from the foundation model to train a lightweight image encoder and a modality controller. Further, they combine with the additionally introduced Self-Patch Prompt Generator (SPPG) and Query-Decoupled Modality Decoder (QDMD) to construct ESP-MedSAM. Specifically, SPPG aims to generate a set of patch prompts automatically and QDMD leverages a one-to-one strategy to provide an independent decoding channel for every modality. Extensive experiments indicate that ESP-MedSAM outperforms state-of-the-arts in diverse medical imaging segmentation takes, displaying superior zero-shot learning and modality transfer ability. Especially, our framework uses only 31.4% parameters compared to SAM-Base.

Segment Anything Model (SAM) has recently shown its powerful effectiveness in visual segmentation tasks. However, there is less exploration concerning how SAM works on audio-visual tasks, such as visual sound localization and segmentation. In this work, we propose a simple yet effective audio-visual localization and segmentation framework based on the Segment Anything Model, namely AV-SAM, that can generate sounding object masks corresponding to the audio. Specifically, our AV-SAM simply leverages pixel-wise audio-visual fusion across audio features and visual features from the pre-trained image encoder in SAM to aggregate cross-modal representations. Then, the aggregated cross-modal features are fed into the prompt encoder and mask decoder to generate the final audio-visual segmentation masks. We conduct extensive experiments on Flickr-SoundNet and AVSBench datasets. The results demonstrate that the proposed AV-SAM can achieve competitive performance on sounding object localization and segmentation.

The goal of this paper is to extract the visual-language correspondence from a pre-trained text-to-image diffusion model, in the form of segmentation map, i.e., simultaneously generating images and segmentation masks for the corresponding visual entities described in the text prompt. We make the following contributions: (i) we pair the existing Stable Diffusion model with a novel grounding module, that can be trained to align the visual and textual embedding space of the diffusion model with only a small number of object categories; (ii) we establish an automatic pipeline for constructing a dataset, that consists of {image, segmentation mask, text prompt} triplets, to train the proposed grounding module; (iii) we evaluate the performance of open-vocabulary grounding on images generated from the text-to-image diffusion model and show that the module can well segment the objects of categories beyond seen ones at training time; (iv) we adopt the augmented diffusion model to build a synthetic semantic segmentation dataset, and show that, training a standard segmentation model on such dataset demonstrates competitive performance on the zero-shot segmentation(ZS3) benchmark, which opens up new opportunities for adopting the powerful diffusion model for discriminative tasks.

In this work, we address various segmentation tasks, each traditionally tackled by distinct or partially unified models. We propose OMG-Seg, One Model that is Good enough to efficiently and effectively handle all the segmentation tasks, including image semantic, instance, and panoptic segmentation, as well as their video counterparts, open vocabulary settings, prompt-driven, interactive segmentation like SAM, and video object segmentation. To our knowledge, this is the first model to handle all these tasks in one model and achieve satisfactory performance. We show that OMG-Seg, a transformer-based encoder-decoder architecture with task-specific queries and outputs, can support over ten distinct segmentation tasks and yet significantly reduce computational and parameter overhead across various tasks and datasets. We rigorously evaluate the inter-task influences and correlations during co-training. Code and models are available at https://github.com/lxtGH/OMG-Seg.

The Segment Anything Model 3 (SAM3) advances visual understanding with Promptable Concept Segmentation (PCS) across images and videos, but its unified architecture (shared vision backbone, DETR-style detector, dense-memory tracker) remains prohibitive for on-device use. We present EfficientSAM3, a family of efficient models built on Progressive Hierarchical Distillation (PHD) that transfers capability from SAM3 to lightweight students in three stages: (1) Encoder Distillation aligns image features via prompt-in-the-loop training on SA-1B; (2) Temporal Memory Distillation replaces dense memory with a compact Perceiver-based module trained on SA-V to compress and retrieve spatiotemporal features efficiently; and (3) End-to-End Fine-Tuning refines the full pipeline on the official SAM3 PCS data to preserve concept-level performance. PHD yields a spectrum of student variants using RepViT, TinyViT, and EfficientViT backbones, enabling on-device concept segmentation and tracking while maintaining high fidelity to teacher behavior. We benchmark on popular VOS datasets, and compare with varies of releated work, achieing strong performance-efficiency trade-offs.

Multi-modal brain tumor segmentation is critical for clinical diagnosis, and it requires accurate identification of distinct internal anatomical subregions. While the recent prompt-based segmentation paradigms enable interactive experiences for clinicians, existing methods ignore cross-modal correlations and rely on labor-intensive category-specific prompts, limiting their applicability in real-world scenarios. To address these issues, we propose a MSM-Seg framework for multi-modal brain tumor segmentation. The MSM-Seg introduces a novel dual-memory segmentation paradigm that synergistically integrates multi-modal and inter-slice information with the efficient category-agnostic prompt for brain tumor understanding. To this end, we first devise a modality-and-slice memory attention (MSMA) to exploit the cross-modal and inter-slice relationships among the input scans. Then, we propose a multi-scale category-agnostic prompt encoder (MCP-Encoder) to provide tumor region guidance for decoding. Moreover, we devise a modality-adaptive fusion decoder (MF-Decoder) that leverages the complementary decoding information across different modalities to improve segmentation accuracy. Extensive experiments on different MRI datasets demonstrate that our MSM-Seg framework outperforms state-of-the-art methods in multi-modal metastases and glioma tumor segmentation. The code is available at https://github.com/xq141839/MSM-Seg.

Zero-shot referring image segmentation aims to locate and segment the target region based on a referring expression, with the primary challenge of aligning and matching semantics across visual and textual modalities without training. Previous works address this challenge by utilizing Vision-Language Models and mask proposal networks for region-text matching. However, this paradigm may lead to incorrect target localization due to the inherent ambiguity and diversity of free-form referring expressions. To alleviate this issue, we present LGD (Leveraging Generative Descriptions), a framework that utilizes the advanced language generation capabilities of Multi-Modal Large Language Models to enhance region-text matching performance in Vision-Language Models. Specifically, we first design two kinds of prompts, the attribute prompt and the surrounding prompt, to guide the Multi-Modal Large Language Models in generating descriptions related to the crucial attributes of the referent object and the details of surrounding objects, referred to as attribute description and surrounding description, respectively. Secondly, three visual-text matching scores are introduced to evaluate the similarity between instance-level visual features and textual features, which determines the mask most associated with the referring expression. The proposed method achieves new state-of-the-art performance on three public datasets RefCOCO, RefCOCO+ and RefCOCOg, with maximum improvements of 9.97% in oIoU and 11.29% in mIoU compared to previous methods.

Recently, large-scale vision-language models such as CLIP have demonstrated immense potential in zero-shot anomaly segmentation (ZSAS) task, utilizing a unified model to directly detect anomalies on any unseen product with painstakingly crafted text prompts. However, existing methods often assume that the product category to be inspected is known, thus setting product-specific text prompts, which is difficult to achieve in the data privacy scenarios. Moreover, even the same type of product exhibits significant differences due to specific components and variations in the production process, posing significant challenges to the design of text prompts. In this end, we propose a visual context prompting model (VCP-CLIP) for ZSAS task based on CLIP. The insight behind VCP-CLIP is to employ visual context prompting to activate CLIP's anomalous semantic perception ability. In specific, we first design a Pre-VCP module to embed global visual information into the text prompt, thus eliminating the necessity for product-specific prompts. Then, we propose a novel Post-VCP module, that adjusts the text embeddings utilizing the fine-grained features of the images. In extensive experiments conducted on 10 real-world industrial anomaly segmentation datasets, VCP-CLIP achieved state-of-the-art performance in ZSAS task. The code is available at https://github.com/xiaozhen228/VCP-CLIP.

The Segment Anything Model (SAM) represents a significant breakthrough into foundation models for computer vision, providing a large-scale image segmentation model. However, despite SAM's zero-shot performance, its segmentation masks lack fine-grained details, particularly in accurately delineating object boundaries. Therefore, it is both interesting and valuable to explore whether SAM can be improved towards highly accurate object segmentation, which is known as the dichotomous image segmentation (DIS) task. To address this issue, we propose DIS-SAM, which advances SAM towards DIS with extremely accurate details. DIS-SAM is a framework specifically tailored for highly accurate segmentation, maintaining SAM's promptable design. DIS-SAM employs a two-stage approach, integrating SAM with a modified advanced network that was previously designed to handle the prompt-free DIS task. To better train DIS-SAM, we employ a ground truth enrichment strategy by modifying original mask annotations. Despite its simplicity, DIS-SAM significantly advances the SAM, HQ-SAM, and Pi-SAM ~by 8.5%, ~6.9%, and ~3.7% maximum F-measure. Our code at https://github.com/Tennine2077/DIS-SAM

In this paper, we propose an embarrassingly simple yet highly effective zero-shot semantic segmentation (ZS3) method, based on the pre-trained vision-language model CLIP. First, our study provides a couple of key discoveries: (i) the global tokens (a.k.a [CLS] tokens in Transformer) of the text branch in CLIP provide a powerful representation of semantic information and (ii) these text-side [CLS] tokens can be regarded as category priors to guide CLIP visual encoder pay more attention on the corresponding region of interest. Based on that, we build upon the CLIP model as a backbone which we extend with a One-Way [CLS] token navigation from text to the visual branch that enables zero-shot dense prediction, dubbed ClsCLIP. Specifically, we use the [CLS] token output from the text branch, as an auxiliary semantic prompt, to replace the [CLS] token in shallow layers of the ViT-based visual encoder. This one-way navigation embeds such global category prior earlier and thus promotes semantic segmentation. Furthermore, to better segment tiny objects in ZS3, we further enhance ClsCLIP with a local zoom-in strategy, which employs a region proposal pre-processing and we get ClsCLIP+. Extensive experiments demonstrate that our proposed ZS3 method achieves a SOTA performance, and it is even comparable with those few-shot semantic segmentation methods.

Recent advances in generative modeling with diffusion processes (DPs) enabled breakthroughs in image synthesis. Despite impressive image quality, these models have various prompt compliance problems, including low recall in generating multiple objects, difficulty in generating text in images, and meeting constraints like object locations and pose. For fine-grained editing and manipulation, they also require fine-grained semantic or instance maps that are tedious to produce manually. While prompt compliance can be enhanced by addition of loss functions at inference, this is time consuming and does not scale to complex scenes. To overcome these limitations, this work introduces a new family of Factor Graph Diffusion Models (FG-DMs) that models the joint distribution of images and conditioning variables, such as semantic, sketch, depth or normal maps via a factor graph decomposition. This joint structure has several advantages, including support for efficient sampling based prompt compliance schemes, which produce images of high object recall, semi-automated fine-grained editing, text-based editing of conditions with noise inversion, explainability at intermediate levels, ability to produce labeled datasets for the training of downstream models such as segmentation or depth, training with missing data, and continual learning where new conditioning variables can be added with minimal or no modifications to the existing structure. We propose an implementation of FG-DMs by adapting a pre-trained Stable Diffusion (SD) model to implement all FG-DM factors, using only COCO dataset, and show that it is effective in generating images with 15\% higher recall than SD while retaining its generalization ability. We introduce an attention distillation loss that encourages consistency among the attention maps of all factors, improving the fidelity of the generated conditions and image.

Few-shot semantic segmentation aims to segment objects from previously unseen classes using only a limited number of labeled examples. In this paper, we introduce Label Anything, a novel transformer-based architecture designed for multi-prompt, multi-way few-shot semantic segmentation. Our approach leverages diverse visual prompts -- points, bounding boxes, and masks -- to create a highly flexible and generalizable framework that significantly reduces annotation burden while maintaining high accuracy. Label Anything makes three key contributions: (i) we introduce a new task formulation that relaxes conventional few-shot segmentation constraints by supporting various types of prompts, multi-class classification, and enabling multiple prompts within a single image; (ii) we propose a novel architecture based on transformers and attention mechanisms; and (iii) we design a versatile training procedure allowing our model to operate seamlessly across different N-way K-shot and prompt-type configurations with a single trained model. Our extensive experimental evaluation on the widely used COCO-20^i benchmark demonstrates that Label Anything achieves state-of-the-art performance among existing multi-way few-shot segmentation methods, while significantly outperforming leading single-class models when evaluated in multi-class settings. Code and trained models are available at https://github.com/pasqualedem/LabelAnything.

Text-conditioned image generation has made significant progress in recent years with generative adversarial networks and more recently, diffusion models. While diffusion models conditioned on text prompts have produced impressive and high-quality images, accurately representing complex text prompts such as the number of instances of a specific object remains challenging. To address this limitation, we propose a novel guidance approach for the sampling process in the diffusion model that leverages bounding box and segmentation map information at inference time without additional training data. Through a novel loss in the sampling process, our approach guides the model with semantic features from CLIP embeddings and enforces geometric constraints, leading to high-resolution images that accurately represent the scene. To obtain bounding box and segmentation map information, we structure the text prompt as a scene graph and enrich the nodes with CLIP embeddings. Our proposed model achieves state-of-the-art performance on two public benchmarks for image generation from scene graphs, surpassing both scene graph to image and text-based diffusion models in various metrics. Our results demonstrate the effectiveness of incorporating bounding box and segmentation map guidance in the diffusion model sampling process for more accurate text-to-image generation.

Recent text-to-image diffusion models are able to generate convincing results of unprecedented quality. However, it is nearly impossible to control the shapes of different regions/objects or their layout in a fine-grained fashion. Previous attempts to provide such controls were hindered by their reliance on a fixed set of labels. To this end, we present SpaText - a new method for text-to-image generation using open-vocabulary scene control. In addition to a global text prompt that describes the entire scene, the user provides a segmentation map where each region of interest is annotated by a free-form natural language description. Due to lack of large-scale datasets that have a detailed textual description for each region in the image, we choose to leverage the current large-scale text-to-image datasets and base our approach on a novel CLIP-based spatio-textual representation, and show its effectiveness on two state-of-the-art diffusion models: pixel-based and latent-based. In addition, we show how to extend the classifier-free guidance method in diffusion models to the multi-conditional case and present an alternative accelerated inference algorithm. Finally, we offer several automatic evaluation metrics and use them, in addition to FID scores and a user study, to evaluate our method and show that it achieves state-of-the-art results on image generation with free-form textual scene control.

We introduce Florence-2, a novel vision foundation model with a unified, prompt-based representation for a variety of computer vision and vision-language tasks. While existing large vision models excel in transfer learning, they struggle to perform a diversity of tasks with simple instructions, a capability that implies handling the complexity of various spatial hierarchy and semantic granularity. Florence-2 was designed to take text-prompt as task instructions and generate desirable results in text forms, whether it be captioning, object detection, grounding or segmentation. This multi-task learning setup demands large-scale, high-quality annotated data. To this end, we co-developed FLD-5B that consists of 5.4 billion comprehensive visual annotations on 126 million images, using an iterative strategy of automated image annotation and model refinement. We adopted a sequence-to-sequence structure to train Florence-2 to perform versatile and comprehensive vision tasks. Extensive evaluations on numerous tasks demonstrated Florence-2 to be a strong vision foundation model contender with unprecedented zero-shot and fine-tuning capabilities.

Surgical video segmentation is crucial for computer-assisted surgery, enabling precise localization and tracking of instruments and tissues. Interactive Video Object Segmentation (iVOS) models such as Segment Anything Model 2 (SAM2) provide prompt-based flexibility beyond methods with predefined categories, but face challenges in surgical scenarios due to the domain gap and limited long-term tracking. To address these limitations, we construct SA-SV, the largest surgical iVOS benchmark with instance-level spatio-temporal annotations (masklets) spanning eight procedure types (61k frames, 1.6k masklets), enabling comprehensive development and evaluation for long-term tracking and zero-shot generalization. Building on SA-SV, we propose SAM2S, a foundation model enhancing SAM2 for Surgical iVOS through: (1) DiveMem, a trainable diverse memory mechanism for robust long-term tracking; (2) temporal semantic learning for instrument understanding; and (3) ambiguity-resilient learning to mitigate annotation inconsistencies across multi-source datasets. Extensive experiments demonstrate that fine-tuning on SA-SV enables substantial performance gains, with SAM2 improving by 12.99 average J\&F over vanilla SAM2. SAM2S further advances performance to 80.42 average J\&F, surpassing vanilla and fine-tuned SAM2 by 17.10 and 4.11 points respectively, while maintaining 68 FPS real-time inference and strong zero-shot generalization. Code and dataset will be released at https://jinlab-imvr.github.io/SAM2S.

Vision systems to see and reason about the compositional nature of visual scenes are fundamental to understanding our world. The complex relations between objects and their locations, ambiguities, and variations in the real-world environment can be better described in human language, naturally governed by grammatical rules and other modalities such as audio and depth. The models learned to bridge the gap between such modalities coupled with large-scale training data facilitate contextual reasoning, generalization, and prompt capabilities at test time. These models are referred to as foundational models. The output of such models can be modified through human-provided prompts without retraining, e.g., segmenting a particular object by providing a bounding box, having interactive dialogues by asking questions about an image or video scene or manipulating the robot's behavior through language instructions. In this survey, we provide a comprehensive review of such emerging foundational models, including typical architecture designs to combine different modalities (vision, text, audio, etc), training objectives (contrastive, generative), pre-training datasets, fine-tuning mechanisms, and the common prompting patterns; textual, visual, and heterogeneous. We discuss the open challenges and research directions for foundational models in computer vision, including difficulties in their evaluations and benchmarking, gaps in their real-world understanding, limitations of their contextual understanding, biases, vulnerability to adversarial attacks, and interpretability issues. We review recent developments in this field, covering a wide range of applications of foundation models systematically and comprehensively. A comprehensive list of foundational models studied in this work is available at https://github.com/awaisrauf/Awesome-CV-Foundational-Models.

Automated feature detection in historical maps can significantly accelerate the reconstruction of the geospatial past. However, this process is often constrained by the time-consuming task of manually digitizing sufficient high-quality training data. The emergence of visual foundation models, such as the Segment Anything Model (SAM), offers a promising solution due to their remarkable generalization capabilities and rapid adaptation to new data distributions. Despite this, directly applying SAM in a zero-shot manner to historical map segmentation poses significant challenges, including poor recognition of certain geospatial features and a reliance on input prompts, which limits its ability to be fully automated. To address these challenges, we introduce MapSAM, a parameter-efficient fine-tuning strategy that adapts SAM into a prompt-free and versatile solution for various downstream historical map segmentation tasks. Specifically, we employ Weight-Decomposed Low-Rank Adaptation (DoRA) to integrate domain-specific knowledge into the image encoder. Additionally, we develop an automatic prompt generation process, eliminating the need for manual input. We further enhance the positional prompt in SAM, transforming it into a higher-level positional-semantic prompt, and modify the cross-attention mechanism in the mask decoder with masked attention for more effective feature aggregation. The proposed MapSAM framework demonstrates promising performance across two distinct historical map segmentation tasks: one focused on linear features and the other on areal features. Experimental results show that it adapts well to various features, even when fine-tuned with extremely limited data (e.g. 10 shots).

Medical image segmentation and video object segmentation are essential for diagnosing and analyzing diseases by identifying and measuring biological structures. Recent advances in natural domain have been driven by foundation models like the Segment Anything Model 2 (SAM 2). To explore the performance of SAM 2 in biomedical applications, we designed two evaluation pipelines for single-frame image segmentation and multi-frame video segmentation with varied prompt designs, revealing SAM 2's limitations in medical contexts. Consequently, we developed BioSAM 2, an enhanced foundation model optimized for biomedical data based on SAM 2. Our experiments show that BioSAM 2 not only surpasses the performance of existing state-of-the-art foundation models but also matches or even exceeds specialist models, demonstrating its efficacy and potential in the medical domain.

Imitation learning and world models have shown significant promise in advancing generalizable robotic learning, with robotic grasping remaining a critical challenge for achieving precise manipulation. Existing methods often rely heavily on robot arm state data and RGB images, leading to overfitting to specific object shapes or positions. To address these limitations, we propose RoboGrasp, a universal grasping policy framework that integrates pretrained grasp detection models with robotic learning. By leveraging robust visual guidance from object detection and segmentation tasks, RoboGrasp significantly enhances grasp precision, stability, and generalizability, achieving up to 34% higher success rates in few-shot learning and grasping box prompt tasks. Built on diffusion-based methods, RoboGrasp is adaptable to various robotic learning paradigms, enabling precise and reliable manipulation across diverse and complex scenarios. This framework represents a scalable and versatile solution for tackling real-world challenges in robotic grasping.

In this paper, we introduce Medical SAM 2 (MedSAM-2), an advanced segmentation model that utilizes the SAM 2 framework to address both 2D and 3D medical image segmentation tasks. By adopting the philosophy of taking medical images as videos, MedSAM-2 not only applies to 3D medical images but also unlocks new One-prompt Segmentation capability. That allows users to provide a prompt for just one or a specific image targeting an object, after which the model can autonomously segment the same type of object in all subsequent images, regardless of temporal relationships between the images. We evaluated MedSAM-2 across a variety of medical imaging modalities, including abdominal organs, optic discs, brain tumors, thyroid nodules, and skin lesions, comparing it against state-of-the-art models in both traditional and interactive segmentation settings. Our findings show that MedSAM-2 not only surpasses existing models in performance but also exhibits superior generalization across a range of medical image segmentation tasks. Our code will be released at: https://github.com/MedicineToken/Medical-SAM2

Following the gaze of other people and analyzing the target they are looking at can help us understand what they are thinking, and doing, and predict the actions that may follow. Existing methods for gaze following struggle to perform well in natural scenes with diverse objects, and focus on gaze points rather than objects, making it difficult to deliver clear semantics and accurate scope of the targets. To address this shortcoming, we propose a novel gaze target prediction solution named GazeSeg, that can fully utilize the spatial visual field of the person as guiding information and lead to a progressively coarse-to-fine gaze target segmentation and recognition process. Specifically, a prompt-based visual foundation model serves as the encoder, working in conjunction with three distinct decoding modules (e.g. FoV perception, heatmap generation, and segmentation) to form the framework for gaze target prediction. Then, with the head bounding box performed as an initial prompt, GazeSeg obtains the FoV map, heatmap, and segmentation map progressively, leading to a unified framework for multiple tasks (e.g. direction estimation, gaze target segmentation, and recognition). In particular, to facilitate this research, we construct and release a new dataset, comprising 72k images with pixel-level annotations and 270 categories of gaze targets, built upon the GazeFollow dataset. The quantitative evaluation shows that our approach achieves the Dice of 0.325 in gaze target segmentation and 71.7% top-5 recognition. Meanwhile, our approach also outperforms previous state-of-the-art methods, achieving 0.953 in AUC on the gaze-following task. The dataset and code will be released.

Medical image segmentation of anatomical structures and pathology is crucial in modern clinical diagnosis, disease study, and treatment planning. To date, great progress has been made in deep learning-based segmentation techniques, but most methods still lack data efficiency, generalizability, and interactability. Consequently, the development of new, precise segmentation methods that demand fewer labeled datasets is of utmost importance in medical image analysis. Recently, the emergence of foundation models, such as CLIP and Segment-Anything-Model (SAM), with comprehensive cross-domain representation opened the door for interactive and universal image segmentation. However, exploration of these models for data-efficient medical image segmentation is still limited, but is highly necessary. In this paper, we propose a novel framework, called MedCLIP-SAM that combines CLIP and SAM models to generate segmentation of clinical scans using text prompts in both zero-shot and weakly supervised settings. To achieve this, we employed a new Decoupled Hard Negative Noise Contrastive Estimation (DHN-NCE) loss to fine-tune the BiomedCLIP model and the recent gScoreCAM to generate prompts to obtain segmentation masks from SAM in a zero-shot setting. Additionally, we explored the use of zero-shot segmentation labels in a weakly supervised paradigm to improve the segmentation quality further. By extensively testing three diverse segmentation tasks and medical image modalities (breast tumor ultrasound, brain tumor MRI, and lung X-ray), our proposed framework has demonstrated excellent accuracy. Code is available at https://github.com/HealthX-Lab/MedCLIP-SAM.

Although perception systems have made remarkable advancements in recent years, particularly in 2D reasoning segmentation, these systems still rely on explicit human instruction or pre-defined categories to identify target objects before executing visual recognition tasks. Such systems have matured significantly, demonstrating the ability to reason and comprehend implicit user intentions in two-dimensional contexts, producing accurate segmentation masks based on complex and implicit query text. However, a comparable framework and structure for 3D reasoning segmentation remain absent. This paper introduces OpenMaskDINO3D, a LLM designed for comprehensive 3D understanding and segmentation. OpenMaskDINO3D processes point cloud data and text prompts to produce instance segmentation masks, excelling in many 3D tasks. By introducing a SEG token and object identifier, we achieve high-precision 3D segmentation mask generation, enabling the model to directly produce accurate point cloud segmentation results from natural language instructions. Experimental results on large-scale ScanNet datasets validate the effectiveness of our OpenMaskDINO3D across various tasks.

We introduce SAMPro3D for zero-shot 3D indoor scene segmentation. Given the 3D point cloud and multiple posed 2D frames of 3D scenes, our approach segments 3D scenes by applying the pretrained Segment Anything Model (SAM) to 2D frames. Our key idea involves locating 3D points in scenes as natural 3D prompts to align their projected pixel prompts across frames, ensuring frame-consistency in both pixel prompts and their SAM-predicted masks. Moreover, we suggest filtering out low-quality 3D prompts based on feedback from all 2D frames, for enhancing segmentation quality. We also propose to consolidate different 3D prompts if they are segmenting the same object, bringing a more comprehensive segmentation. Notably, our method does not require any additional training on domain-specific data, enabling us to preserve the zero-shot power of SAM. Extensive qualitative and quantitative results show that our method consistently achieves higher quality and more diverse segmentation than previous zero-shot or fully supervised approaches, and in many cases even surpasses human-level annotations. The project page can be accessed at https://mutianxu.github.io/sampro3d/.

Recent Large Vision Language Models (LVLMs) demonstrate promising capabilities in unifying visual understanding and generative modeling, enabling both accurate content understanding and flexible editing. However, current approaches treat "what to see" and "how to edit" separately: they either perform isolated object segmentation or utilize segmentation masks merely as conditional prompts for local edit generation tasks, often relying on multiple disjointed models. To bridge these gaps, we introduce FOCUS, a unified LVLM that integrates segmentation-aware perception and controllable object-centric generation within an end-to-end framework. FOCUS employs a dual-branch visual encoder to simultaneously capture global semantic context and fine-grained spatial details. In addition, we leverage a MoVQGAN-based visual tokenizer to produce discrete visual tokens that enhance generation quality. To enable accurate and controllable image editing, we propose a progressive multi-stage training pipeline, where segmentation masks are jointly optimized and used as spatial condition prompts to guide the diffusion decoder. This strategy aligns visual encoding, segmentation, and generation modules, effectively bridging segmentation-aware perception with fine-grained visual synthesis. Extensive experiments across three core tasks, including multimodal understanding, referring segmentation accuracy, and controllable image generation, demonstrate that FOCUS achieves strong performance by jointly optimizing visual perception and generative capabilities.

Multi-modal Large Language Models (MLLMs) have demonstrated remarkable reasoning capability while lack explicit mechanisms for visual grounding and segmentation, creating a gap between cognitive reasoning and visual perception. To bridge this gap, we introduce Reasoning Segmentation via Visual Prompting (RSVP), a novel framework that unifies multi-step multimodal reasoning with grounded visual understanding. RSVP is a two-stage structuralized framework that integrates reasoning-driven localization with segmentation refinement. In the reasoning stage, RSVP employs multimodal chain-of-thought visual prompts to help MLLMs understand queries and infer targets, generating interpretable region proposals that enhance visual grounding. In segmentation stage, RSVP refines these proposals with a Vision-Language Segmentation Module (VLSM), seamlessly integrates textual and visual cues to produce precise segmentation masks. By explicitly modelling the interaction between multimodal reasoning and segmentation, RSVP introduces a new paradigm for interpretable reasoning segmentation. It exploits MLLMs' inherent localization capabilities, enabling the models to not only reason about objects but also generate structured visual representations. Our extensive experiments demonstrate that RSVP achieves state-of-the-art performance, surpasses state-of-the-art methods by up to +6.5 gIoU and +9.2 cIoU on ReasonSeg, and achieves 49.7 mAP on SegInW under zero-shot settings. These results validate RSVP as an effective and scalable framework for integrating cognitive reasoning with structured visual understanding.

Recent works on open-vocabulary 3D instance segmentation show strong promise, but at the cost of slow inference speed and high computation requirements. This high computation cost is typically due to their heavy reliance on 3D clip features, which require computationally expensive 2D foundation models like Segment Anything (SAM) and CLIP for multi-view aggregation into 3D. As a consequence, this hampers their applicability in many real-world applications that require both fast and accurate predictions. To this end, we propose a fast yet accurate open-vocabulary 3D instance segmentation approach, named Open-YOLO 3D, that effectively leverages only 2D object detection from multi-view RGB images for open-vocabulary 3D instance segmentation. We address this task by generating class-agnostic 3D masks for objects in the scene and associating them with text prompts. We observe that the projection of class-agnostic 3D point cloud instances already holds instance information; thus, using SAM might only result in redundancy that unnecessarily increases the inference time. We empirically find that a better performance of matching text prompts to 3D masks can be achieved in a faster fashion with a 2D object detector. We validate our Open-YOLO 3D on two benchmarks, ScanNet200 and Replica, under two scenarios: (i) with ground truth masks, where labels are required for given object proposals, and (ii) with class-agnostic 3D proposals generated from a 3D proposal network. Our Open-YOLO 3D achieves state-of-the-art performance on both datasets while obtaining up to sim16times speedup compared to the best existing method in literature. On ScanNet200 val. set, our Open-YOLO 3D achieves mean average precision (mAP) of 24.7\% while operating at 22 seconds per scene. Code and model are available at github.com/aminebdj/OpenYOLO3D.

Semantic segmentation is a critical technique for effective scene understanding. Traditional RGB-T semantic segmentation models often struggle to generalize across diverse scenarios due to their reliance on pretrained models and predefined categories. Recent advancements in Visual Language Models (VLMs) have facilitated a shift from closed-set to open-vocabulary semantic segmentation methods. However, these models face challenges in dealing with intricate scenes, primarily due to the heterogeneity between RGB and thermal modalities. To address this gap, we present Open-RGBT, a novel open-vocabulary RGB-T semantic segmentation model. Specifically, we obtain instance-level detection proposals by incorporating visual prompts to enhance category understanding. Additionally, we employ the CLIP model to assess image-text similarity, which helps correct semantic consistency and mitigates ambiguities in category identification. Empirical evaluations demonstrate that Open-RGBT achieves superior performance in diverse and challenging real-world scenarios, even in the wild, significantly advancing the field of RGB-T semantic segmentation.

The Segment Anything Model 2 (SAM 2) is the latest generation foundation model for image and video segmentation. Trained on the expansive Segment Anything Video (SA-V) dataset, which comprises 35.5 million masks across 50.9K videos, SAM 2 advances its predecessor's capabilities by supporting zero-shot segmentation through various prompts (e.g., points, boxes, and masks). Its robust zero-shot performance and efficient memory usage make SAM 2 particularly appealing for surgical tool segmentation in videos, especially given the scarcity of labeled data and the diversity of surgical procedures. In this study, we evaluate the zero-shot video segmentation performance of the SAM 2 model across different types of surgeries, including endoscopy and microscopy. We also assess its performance on videos featuring single and multiple tools of varying lengths to demonstrate SAM 2's applicability and effectiveness in the surgical domain. We found that: 1) SAM 2 demonstrates a strong capability for segmenting various surgical videos; 2) When new tools enter the scene, additional prompts are necessary to maintain segmentation accuracy; and 3) Specific challenges inherent to surgical videos can impact the robustness of SAM 2.

Detecting changes between images is a fundamental problem in computer vision with broad applications in situational awareness, infrastructure assessment, environment monitoring, and industrial automation. Existing supervised models are typically limited to detecting specific types of changes, necessitating retraining for new tasks. To address these limitations with a single approach, we propose a novel change detection method that is the first to utilize unaligned images and textual prompts to output a binary segmentation of changes relevant to user-provided text. Our architecture not only enables flexible detection across diverse change detection use cases, but also yields state-of-the art performance on established benchmarks. Additionally, we release an accompanying dataset comprising of 100,311 pairs of images with text prompts and the corresponding change detection labels. We demonstrate the effectiveness of our method both quantitatively and qualitatively on datasets with a wide variety of viewpoints in indoor, outdoor, street level, synthetic, and satellite images.

This research explores the integration of large language models (LLMs) into scientific data assimilation, focusing on combustion science as a case study. Leveraging foundational models integrated with Retrieval-Augmented Generation (RAG) framework, the study introduces an approach to process diverse combustion research data, spanning experimental studies, simulations, and literature. The multifaceted nature of combustion research emphasizes the critical role of knowledge processing in navigating and extracting valuable information from a vast and diverse pool of sources. The developed approach minimizes computational and economic expenses while optimizing data privacy and accuracy. It incorporates prompt engineering and offline open-source LLMs, offering user autonomy in selecting base models. The study provides a thorough examination of text segmentation strategies, conducts comparative studies between LLMs, and explores various optimized prompts to demonstrate the effectiveness of the framework. By incorporating an external database, the framework outperforms a conventional LLM in generating accurate responses and constructing robust arguments. Additionally, the study delves into the investigation of optimized prompt templates for the purpose of efficient extraction of scientific literature. The research addresses concerns related to hallucinations and false research articles by introducing a custom workflow developed with a detection algorithm to filter out inaccuracies. Despite identified areas for improvement, the framework consistently delivers accurate domain-specific responses with minimal human oversight. The prompt-agnostic approach introduced holds promise for future deliberations. The study underscores the significance of integrating LLMs and knowledge processing techniques in scientific research, providing a foundation for advancements in data assimilation and utilization.

We present LlamaSeg, a visual autoregressive framework that unifies multiple image segmentation tasks via natural language instructions. We reformulate image segmentation as a visual generation problem, representing masks as "visual" tokens and employing a LLaMA-style Transformer to predict them directly from image inputs. By adhering to the next-token prediction paradigm, our approach naturally integrates segmentation tasks into autoregressive architectures. To support large-scale training, we introduce a data annotation pipeline and construct the SA-OVRS dataset, which contains 2M segmentation masks annotated with over 5,800 open-vocabulary labels or diverse textual descriptions, covering a wide spectrum of real-world scenarios. This enables our model to localize objects in images based on text prompts and to generate fine-grained masks. To more accurately evaluate the quality of masks produced by visual generative models, we further propose a composite metric that combines Intersection over Union (IoU) with Average Hausdorff Distance (AHD), offering a more precise assessment of contour fidelity. Experimental results demonstrate that our method surpasses existing generative models across multiple datasets and yields more detailed segmentation masks.

Task-generic promptable image segmentation aims to achieve segmentation of diverse samples under a single task description by utilizing only one task-generic prompt. Current methods leverage the generalization capabilities of Vision-Language Models (VLMs) to infer instance-specific prompts from these task-generic prompts in order to guide the segmentation process. However, when VLMs struggle to generalise to some image instances, predicting instance-specific prompts becomes poor. To solve this problem, we introduce Instance-specific Negative Mining for Task-Generic Promptable Segmentation (INT). The key idea of INT is to adaptively reduce the influence of irrelevant (negative) prior knowledge whilst to increase the use the most plausible prior knowledge, selected by negative mining with higher contrast, in order to optimise instance-specific prompts generation. Specifically, INT consists of two components: (1) instance-specific prompt generation, which progressively fliters out incorrect information in prompt generation; (2) semantic mask generation, which ensures each image instance segmentation matches correctly the semantics of the instance-specific prompts. INT is validated on six datasets, including camouflaged objects and medical images, demonstrating its effectiveness, robustness and scalability.

Foundation Vision-Language Models (VLMs) trained using large-scale open-domain images and text pairs have recently been adapted to develop Vision-Language Segmentation Models (VLSMs) that allow providing text prompts during inference to guide image segmentation. If robust and powerful VLSMs can be built for medical images, it could aid medical professionals in many clinical tasks where they must spend substantial time delineating the target structure of interest. VLSMs for medical images resort to fine-tuning base VLM or VLSM pretrained on open-domain natural image datasets due to fewer annotated medical image datasets; this fine-tuning is resource-consuming and expensive as it usually requires updating all or a significant fraction of the pretrained parameters. Recently, lightweight blocks called adapters have been proposed in VLMs that keep the pretrained model frozen and only train adapters during fine-tuning, substantially reducing the computing resources required. We introduce a novel adapter, VLSM-Adapter, that can fine-tune pretrained vision-language segmentation models using transformer encoders. Our experiments in widely used CLIP-based segmentation models show that with only 3 million trainable parameters, the VLSM-Adapter outperforms state-of-the-art and is comparable to the upper bound end-to-end fine-tuning. The source code is available at: https://github.com/naamiinepal/vlsm-adapter.

Segmentation of anatomical structures and pathological regions in medical images is essential for modern clinical diagnosis, disease research, and treatment planning. While significant advancements have been made in deep learning-based segmentation techniques, many of these methods still suffer from limitations in data efficiency, generalizability, and interactivity. As a result, developing precise segmentation methods that require fewer labeled datasets remains a critical challenge in medical image analysis. Recently, the introduction of foundation models like CLIP and Segment-Anything-Model (SAM), with robust cross-domain representations, has paved the way for interactive and universal image segmentation. However, further exploration of these models for data-efficient segmentation in medical imaging is still needed and highly relevant. In this paper, we introduce MedCLIP-SAMv2, a novel framework that integrates the CLIP and SAM models to perform segmentation on clinical scans using text prompts, in both zero-shot and weakly supervised settings. Our approach includes fine-tuning the BiomedCLIP model with a new Decoupled Hard Negative Noise Contrastive Estimation (DHN-NCE) loss, and leveraging the Multi-modal Information Bottleneck (M2IB) to create visual prompts for generating segmentation masks from SAM in the zero-shot setting. We also investigate using zero-shot segmentation labels within a weakly supervised paradigm to enhance segmentation quality further. Extensive testing across four diverse segmentation tasks and medical imaging modalities (breast tumor ultrasound, brain tumor MRI, lung X-ray, and lung CT) demonstrates the high accuracy of our proposed framework. Our code is available at https://github.com/HealthX-Lab/MedCLIP-SAMv2.

Medical image segmentation has recently demonstrated impressive progress with deep neural networks, yet the heterogeneous modalities and scarcity of mask annotations limit the development of segmentation models on unannotated modalities. This paper investigates a new paradigm for leveraging generative models in medical applications: controllably synthesizing data for unannotated modalities, without requiring registered data pairs. Specifically, we make the following contributions in this paper: (i) we collect and curate a large-scale radiology image-text dataset, MedGen-1M, comprising modality labels, attributes, region, and organ information, along with a subset of organ mask annotations, to support research in controllable medical image generation; (ii) we propose a diffusion-based data engine, termed MRGen, which enables generation conditioned on text prompts and masks, synthesizing MR images for diverse modalities lacking mask annotations, to train segmentation models on unannotated modalities; (iii) we conduct extensive experiments across various modalities, illustrating that our data engine can effectively synthesize training samples and extend MRI segmentation towards unannotated modalities.

In this work, we present SEEM, a promptable and interactive model for segmenting everything everywhere all at once in an image, as shown in Fig.1. In SEEM, we propose a novel decoding mechanism that enables diverse prompting for all types of segmentation tasks, aiming at a universal segmentation interface that behaves like large language models (LLMs). More specifically, SEEM is designed with four desiderata: i) Versatility. We introduce a new visual prompt to unify different spatial queries including points, boxes, scribbles and masks, which can further generalize to a different referring image; ii) Compositionality. We learn a joint visual-semantic space between text and visual prompts, which facilitates the dynamic composition of two prompt types required for various segmentation tasks; iii) Interactivity. We further incorporate learnable memory prompts into the decoder to retain segmentation history through mask-guided cross-attention from decoder to image features; and iv) Semantic-awareness. We use a text encoder to encode text queries and mask labels into the same semantic space for open-vocabulary segmentation. We conduct a comprehensive empirical study to validate the effectiveness of SEEM across diverse segmentation tasks. Notably, our single SEEM model achieves competitive performance across interactive segmentation, generic segmentation, referring segmentation, and video object segmentation on 9 datasets with minimum 1/100 supervision. Furthermore, SEEM showcases a remarkable capacity for generalization to novel prompts or their combinations, rendering it a readily universal image segmentation interface.